Clinical trialNCT00335660TerminatedPhase 2Interventional

Safety and Efficacy of AV608 in Subjects With Idiopathic Detrusor Overactivity

SponsorAvera PharmaceuticalsEnrollment62Overactive Bladder Syndrome

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to assess the effects of AV608, a neurokinin 1 (NK-1) antagonist, in subjects with Idiopathic Detrusor Overactivity.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Joao Siffert, MD
Avera Pharmaceuticals, Inc.
Study Director
clinicaltrials.gov ↗
Linda Cardozo, MD FRCOG
King's College Hospital NHS Trust
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

13 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Netherlands

Facility name not stated
Amsterdam, Netherlands
Facility name not stated
Nieuwegein, Netherlands
Facility name not stated
Zeist, Netherlands

United Kingdom

Facility name not stated
Birmingham, England, United Kingdom
Facility name not stated
Blackburn, England, United Kingdom
Facility name not stated
Chertsey, England, United Kingdom
Facility name not stated
Hull, England, United Kingdom
Facility name not stated
Leeds, England, United Kingdom
Facility name not stated
Liverpool, England, United Kingdom
Facility name not stated
London, England, United Kingdom
Facility name not stated
Plymouth, England, United Kingdom
Facility name not stated
Sheffield, England, United Kingdom
Facility name not stated
Falkirk, Scotland, United Kingdom

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

AV608

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 30 Jun 2006
Primary completion: 30 Jun 2007
Completion: 30 Sept 2007
Last update posted: 25 Feb 2008
Registered enrollment: 62
Registry id: NCT00335660

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.