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Clinical trialNCT00387829TerminatedInterventional

DuraGen Plus® Adhesion Barrier for Use in Spinal Surgery

SponsorIntegra LifeSciences CorporationEnrollment347AdhesionsSpinal Injuries
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

To evaluate the safety and effectiveness of DuraGen Plus® Adhesion Barrier Matrix as an adhesion barrier in spinal surgery to reduce the extent of peridural fibrosis formation and radicular pain in comparison to a control group receiving standard care.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

36 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Ronderos Neurosurgery Center, Providence Hospital

    Mobile, Alabama, United States

  • Spine Source

    Beverly Hills, California, United States

  • Cedars-Sinai Medical Center

    Los Angeles, California, United States

  • Mission Hospital

    Mission Viejo, California, United States

  • University of California, San Diego

    San Diego, California, United States

  • Spine Institute

    Santa Monica, California, United States

  • Southern California Orthopedic Institute

    Van Nuys, California, United States

  • Greenwich Neurosurgery/greenwich Hospital

    Greenwich, Connecticut, United States

  • Orthopaedic Specialties Spine Center

    Clearwater, Florida, United States

  • the Back Center

    Melbourne, Florida, United States

  • University of Miami

    Miami, Florida, United States

  • Tallahassee Neurological Clinic

    Tallahassee, Florida, United States

  • University of South Florida

    Tampa, Florida, United States

  • Southeastern Orthopedic Center

    Savannah, Georgia, United States

  • Chicago Institute of Neurosurgery and Neuroresearch

    Chicago, Illinois, United States

  • Northwestern University

    Chicago, Illinois, United States

  • Osf Saint Francis Medical Center

    Peoria, Illinois, United States

  • Bluegrass Orthopedics

    Lexington, Kentucky, United States

  • Interactive Neuroscience Center

    Shreveport, Louisiana, United States

  • Johns Hopkins Hospital

    Baltimore, Maryland, United States

  • Columbia Orthopedic Group

    Columbia, Missouri, United States

  • Montana Neuroscience Institute Foundation

    Missoula, Montana, United States

  • William S. Muir, Md, Pc

    Las Vegas, Nevada, United States

  • University of Medicine and Dentistry of New Jersey

    New Brunswick, New Jersey, United States

  • University of Cincinnati Medical Center / Mayfield Clinic

    Cincinnati, Ohio, United States

  • the Cleveland Clinic Spine Institute

    Cleveland, Ohio, United States

  • Central Ohio Neurological Surgery

    Westerville, Ohio, United States

  • Penn State Milton S. Hershey Medical Center

    Hershey, Pennsylvania, United States

  • Princeton Brain and Spine Care

    Langhorne, Pennsylvania, United States

  • Hospital of the University of Pennsylvania

    Philadelphia, Pennsylvania, United States

  • Roger Williams Hospital

    Providence, Rhode Island, United States

  • Texas Back Institute

    Plano, Texas, United States

  • University of Virginia

    Charlottesville, Virginia, United States

  • Virginia Commonwealth University Health System

    Richmond, Virginia, United States

  • Orthopedics Intl.

    Seattle, Washington, United States

  • Swedish Neuroscience Institute

    Seattle, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 Oct 2006
Primary completion
31 Dec 2010
Completion
31 Dec 2011
Last update posted
7 Sept 2017
Registered enrollment
347
Registry id
NCT00387829

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.