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Clinical trialNCT00400634CompletedPhase 2Interventional

Double-Blind, Multicenter, Sham Surgery Controlled Study of CERE-120 in Subjects With Idiopathic Parkinson's Disease

SponsorSangamo TherapeuticsEnrollment58Idiopathic Parkinson's Disease
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this double blind study is to determine whether CERE-120 (adeno-associated virus serotype 2 \[AAV2\]-neurturin \[NTN\]) is effective and safe in the treatment of patients with idiopathic Parkinson's Disease. CERE-120 is administered via bilateral stereotactic injections targeting the putaminal region of the brain. The design of this study involves approximately 34 patients receiving CERE-120 treatment via stereotactic surgery and approximately 17 patients receiving sham stereotactic surgery (no CERE-120 administered).
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

9 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • University of Alabama, Birmingham

    Birmingham, Alabama, United States

  • University of California, San Francisco

    San Francisco, California, United States

  • Rush University Medical Center

    Chicago, Illinois, United States

  • Mount Sinai School of Medicine

    New York, New York, United States

  • Duke University Medical Center

    Durham, North Carolina, United States

  • Cleveland Clinic

    Cleveland, Ohio, United States

  • Oregon Health and Science University

    Portland, Oregon, United States

  • Pennsylvania Hospital

    Philadelphia, Pennsylvania, United States

  • Baylor College of Medicine

    Houston, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

CERE-120
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
30 Nov 2006
Primary completion
30 Nov 2008
Completion
30 Nov 2008
Last update posted
10 Nov 2022
Registered enrollment
58
Registry id
NCT00400634
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.