Clinical trialNCT00431964CompletedPhase 4Interventional

Effect of Azithromycin on Lung Function in 6-18 Year-olds With Cystic Fibrosis (CF) Not Infected With P. Aeruginosa

SponsorCF Therapeutics Development Network Coordinating CenterEnrollment263Cystic Fibrosis

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is a study to examine the safety, effect on lung function, and frequency of symptoms relating to cystic fibrosis during 24 weeks of treatment with the antibiotic azithromycin in 6-18 year-olds with CF who are not infected with Pseudomonas aeruginosa.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Felix Ratjen, MD
The Hospital for Sick Children, Toronto, Ontario
Principal Investigator
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Larry Lands, MD
Montreal Children's Hospital of the MUHC
Principal Investigator
clinicaltrials.gov ↗
Lisa Saiman, MD, MPH
Columbia University
Principal Investigator
clinicaltrials.gov ↗
Michael Anstead, MD
University of Kentucky
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

40 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada

Alberta Children'S Hospital
Calgary, Alberta, Canada
Bc Children'S Hospital
Vancouver, British Columbia, Canada
Janeway Children'S Health & Rehabilitation Hospital
St. John's, Newfoundland and Labrador, Canada
Mcmaster Health Sciences Centre
Hamilton, Ontario, Canada
Bryan Lyttle, Md, Private Practice
London, Ontario, Canada
Children'S Hospital of Eastern Ontario
Ottawa, Ontario, Canada
the Hospital for Sick Children
Toronto, Ontario, Canada
Csss de Chicoutimi
Chicoutimi, Quebec, Canada
Montreal Children'S Hospital
Montreal, Quebec, Canada

United States

Phoenix Children'S Hospital
Phoenix, Arizona, United States
Connecticut Children'S Medical Center
Hartford, Connecticut, United States
Emory University
Atlanta, Georgia, United States
Children'S Memorial Hospital
Chicago, Illinois, United States
Riley Hospital for Children
Indianapolis, Indiana, United States
University of Kentucky
Lexington, Kentucky, United States
Children'S Hospital Boston
Boston, Massachusetts, United States
University of Michigan
Ann Arbor, Michigan, United States
University of Minnesota
Minneapolis, Minnesota, United States
Children'S Mercy Hospital
Kansas City, Missouri, United States
Washington University
St Louis, Missouri, United States
University of Nebraska Medical Center - Pediatric Pulmonary
Omaha, Nebraska, United States
Dartmouth Hitchcock Medical Center
Lebanon, New Hampshire, United States
Columbia University
New York, New York, United States
University of Rochester Medical Center
Rochester, New York, United States
Suny Upstate Medical University
Syracuse, New York, United States
New York Medical College
Valhalla, New York, United States
Unc Chapel Hill
Chapel Hill, North Carolina, United States
Cincinnati Children'S Hospital
Cincinnati, Ohio, United States
Nationwide Children'S Hospital
Columbus, Ohio, United States
St. Christopher'S Hospital for Children
Philadelphia, Pennsylvania, United States
the Children'S Hospital of Philadelphia
Philadelphia, Pennsylvania, United States
Children'S Hospital of Pittsburgh, Pulmonary Medicine, Allergy & Immunology
Pittsburgh, Pennsylvania, United States
East Tennessee Children'S Hospital, Pediatric Pulmonary & Respiratory Care
Knoxville, Tennessee, United States
University of Tennessee Health Science Center
Memphis, Tennessee, United States
Vanderbilt Children'S Hospital
Nashville, Tennessee, United States
University of Utah Pediatric Pulmonology
Salt Lake City, Utah, United States
Vermont Children'S Hospital
Burlington, Vermont, United States
University of Virginia at Charlottesville Children'S Hospital
Charlottesville, Virginia, United States
West Virginia University
Morgantown, West Virginia, United States
Children'S Hospital of Wisconsin
Milwaukee, Wisconsin, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Azithromycin →Placebo

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 28 Feb 2007
Primary completion: 31 Jul 2009
Completion: 30 Nov 2009
Last update posted: 19 Aug 2015
Registered enrollment: 263
Registry id: NCT00431964

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.