Clinical trialNCT00436332CompletedPhase 2Interventional

S0635: Erlotinib and Bevacizumab in Stage IIIB and IV Bronchioloalveolar Carcinoma

SponsorSWOG Cancer Research NetworkEnrollment84Lung Cancer

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

RATIONALE: Erlotinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Bevacizumab may also stop the growth of tumor cells by blocking blood flow to the tumor. Giving erlotinib together with bevacizumab may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving erlotinib together with bevacizumab works in treating patients with stage III or stage IV non-small cell lung cancer.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Howard L. West, MD
Swedish Cancer Institute at Swedish Medical Center - First Hill Campus
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

148 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Kaiser Permanente - Deer Valley
Antioch, California, United States
Alta Bates Summit Comprehensive Cancer Center
Berkeley, California, United States
Peninsula Medical Center
Burlingame, California, United States
Kaiser Permanente - Fremont
Fremont, California, United States
Kaiser Permanente Medical Center - Hayward
Hayward, California, United States
Tibotec Therapeutics - Division of Ortho Biotech Products, Lp
Marysville, California, United States
Kaiser Permanente Medical Center - Oakland
Oakland, California, United States
Valley Medical Oncology Consultants - Pleasanton
Pleasanton, California, United States
Kaiser Permanente Medical Center - Redwood City
Redwood City, California, United States
Kaiser Permanente Medical Center - Richmond
Richmond, California, United States
Kaiser Permanente Medical Center - Roseville
Roseville, California, United States
Kaiser Permanente Medical Center - Sacramento
Sacramento, California, United States
South Sacramento Kaiser-Permanente Medical Center
Sacramento, California, United States
University of California Davis Cancer Center
Sacramento, California, United States
California Pacific Medical Center - California Campus
San Francisco, California, United States
Kaiser Permanente Medical Center - San Francisco Geary Campus
San Francisco, California, United States
Kaiser Permanente Medical Center - Santa Teresa
San Jose, California, United States
Kaiser Foundation Hospital - San Rafael
San Rafael, California, United States
Sutter Health - Western Division Cancer Research Group
San Rafael, California, United States
Kaiser Permanente Medical Center - Santa Clara Kiely Campus
Santa Clara, California, United States
Kaiser Permanente Medical Center - Santa Rosa
Santa Rosa, California, United States
Kaiser Permanente Medical Center - South San Francisco
South San Francisco, California, United States
Kaiser Permanente Medical Facility - Stockton
Stockton, California, United States
Tahoe Forest Cancer Center
Truckee, California, United States
Kaiser Permanente Medical Center - Vacaville
Vacaville, California, United States
Kaiser Permanente Medical Center - Vallejo
Vallejo, California, United States
Sutter Solano Medical Center
Vallejo, California, United States
Kaiser Permanente Medical Center - Walnut Creek
Walnut Creek, California, United States
Saint Francis/mount Sinai Regional Cancer Center at Saint Francis Hospital and Medical Center
Hartford, Connecticut, United States
Ccop - Atlanta Regional
Atlanta, Georgia, United States
Northside Hospital Cancer Center
Atlanta, Georgia, United States
Piedmont Hospital
Atlanta, Georgia, United States
Saint Joseph'S Hospital of Atlanta
Atlanta, Georgia, United States
Wellstar Cobb Hospital
Austell, Georgia, United States
John B. Amos Cancer Center
Columbus, Georgia, United States
Charles B. Eberhart Cancer Center at Dekalb Medical Center
Decatur, Georgia, United States
Piedmont Fayette Hospital
Fayetteville, Georgia, United States
Northeast Georgia Medical Center
Gainesville, Georgia, United States
Gwinnett Medical Center
Lawrenceville, Georgia, United States
Kennestone Cancer Center at Wellstar Kennestone Hospital
Marietta, Georgia, United States

108 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Bevacizumab →Erlotinib →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Jul 2007
Primary completion: 20 Jul 2019
Completion: 20 Aug 2019
Last update posted: 2 Apr 2020
Registered enrollment: 84
Registry id: NCT00436332

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.