Clinical trialNCT00442676WithdrawnPhase 2Interventional

Clinical Trial of a COX-2 Inhibitor for the Treatment of Women With Preeclampsia

SponsorVirginia Commonwealth UniversityEnrollment0Preeclampsia

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Preeclampsia is a hypertensive disorder of pregnancy and a leading cause of fetal and maternal morbidity and mortality. Recent findings indicate preeclampsia is an inflammatory disorder associated with increased expression of COX-2. This study will test the hypothesis that treatment of women with a COX-2 inhibitor, celecoxib, will stop the inflammatory process and reverse symptoms of preeclampsia.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Fidelma B Rigby, MD
Virginia Commonwealth University
Study Director
clinicaltrials.gov ↗
Nicole W Karjane, MD
Virginia Commonwealth University
Study Director
clinicaltrials.gov ↗
Scott W Walsh, PhD
Virginia Commonwealth University
Principal Investigator
clinicaltrials.gov ↗
Susan M Lanni, MD
Virginia Commonwealth University
Study Director
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Mcv Main Hospital
Richmond, Virginia, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Celecoxib →Placebo

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 30 Jun 2009
Primary completion: 31 Jan 2010
Completion: 31 Jan 2010
Last update posted: 13 Mar 2012
Registered enrollment: 0
Registry id: NCT00442676

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.