Study of the Efficacy and Safety of Tezosentan in Patients With Pre-operative Pulmonary Hypertension, Due to Left Heart Disease, Undergoing Open Heart Surgery
Summary
The lay summary the sponsor registered on ClinicalTrials.gov.
Investigators
The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.
- Andre Denault, Prof.
Montreal Heart Institute
Study Chair - Andrea D'Armini, Prof.
San Matteo Hospital
Study Chair - Rainald Seitelberger, Prof.
AKH University of Vienna
Study Chair - Ronald Pearl, MD
Stanford University
Study Chair - Steven Tsui
Papworth Hospital NHS Foundation Trust
Study Chair
A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.
Sites
33 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.
- Medical University of Innsbruck
Innsbruck, Austria
- Akh University of Vienna
Vienna, Austria
- University of Alberta Hospital
Edmonton, Alberta, Canada
- London Health Sciences Centre-University Hospital
London, Ontario, Canada
- Toronto General Hospital
Toronto, Ontario, Canada
- Montreal Heart Institute
Montreal, Quebec, Canada
- Quebec Heart Institute/hopital Laval
Québec, Quebec, Canada
- Institute for Clinical and Experimental Medicine (ikem)
Prague, Czechia
- Hopital Pitie Salpetriere
Paris, France
- Deutches Herzzentrum
Berlin, Germany
- Dresden Universitatsklinik/cardiology Center
Dresden, Germany
- Zentrum Der Chirugie-Zchir-Des Universitatsklinikums
Frankfurt, Germany
- Narayana Hrudayalaya
Bangalore, India
- Nizam'S Institute of Medical Sciences
Hyderabaad, India
- Shaare Zedek Medical Center
Jerusalem, Israel
- Fondazione Irccs San Matteo Hospital, Cardiac Surgery
Pavia, Italy
- Azienda Sanitaria Ospedaliera "san Giovanni Battista", Cardiac Surgery Division
Torino, Italy
- Medical University of Silesia, 2nd Dept of Cardiac Surgery
Katowice, Poland
- Klinika Chirurgii Serca, Naczyn I Transplantologii, Szpital Jana Pawla Ii
Krakow, Poland
- Dedinje Cardiovascular Institute
Belgrade, Serbia
- National Institute of Cardiovascular Diseases, Clinic of Heart Surgery
Bratislava, Slovakia
- Sahlgrenska University Hospital
Gothenburg, Sweden
- Papworth Hospital
Cambridge, United Kingdom
- Northern General Hospital
Sheffield, United Kingdom
- Stanford University School of Medicine
Stanford, California, United States
- Columbia University Medical Center
New York, New York, United States
- Montefiore Medical Center/albert Einstein College of Medicine
New York, New York, United States
- Duke University Medical Center
Durham, North Carolina, United States
- Wake Forest University Health Sciences
Winston-Salem, North Carolina, United States
- the Cleveland Clinic
Cleveland, Ohio, United States
- Baylor University Medical Center
Dallas, Texas, United States
- Texas Heart Institute/st. Luke'S Episcopal Hospital/baylor College
Houston, Texas, United States
- University of Virginia Health System
Charlottesville, Virginia, United States
Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.
Drugs studied
The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.
Registration & key dates
Registry attributes as recorded on the ClinicalTrials.gov study record.
- Start
- 30 Apr 2007
- Primary completion
- 29 Feb 2008
- Completion
- 31 Mar 2008
- Last update posted
- 9 Jul 2018
- Registered enrollment
- 274
- Registry id
- NCT00458276
Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.