FindMyKOL
Clinical trialNCT00491699TerminatedPhase 1Interventional

Safety Study of XL999 in Adults With Non-Small-Cell Lung Cancer

SponsorSymphony Evolution, Inc.Enrollment2Non-Small-Cell Lung Cancer
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to determine the safest dose of XL999 and how well subjects with Non-Small-Cell Lung Cancer tolerate XL999. XL999 is a small molecule inhibitor of multiple kinases including VEGFR, PDGFR, FGFR, FLT-3, and Src, which are involved in tumor cell growth, formation of new blood vessels (angiogenesis), and metastasis.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

5 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Ucla Medical Center

    Los Angeles, California, United States

  • Peachtree Hematology Oncology Consultants

    Atlanta, Georgia, United States

  • Wayne State University, Karmanos Cancer Institute

    Detroit, Michigan, United States

  • Hematology-Oncology Associates of Rockland

    Nyack, New York, United States

  • Cancer Therapy and Research Center at the Ut Health Science Center at San Antonio

    San Antonio, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

XL999
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 Aug 2007
Primary completion
31 Jan 2008
Completion
31 May 2008
Last update posted
19 Feb 2010
Registered enrollment
2
Registry id
NCT00491699
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.