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Clinical trialNCT00495144CompletedPhase 1Interventional

A Phase I Study of the Safety, Pharmacokinetics, and Anti-Tumor Activity of TH-302 in Patients With Advanced Solid Tumors

SponsorThreshold PharmaceuticalsEnrollment129HypoxiaTumors
View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

7 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Mayo Clinic Arizona

    Scottsdale, Arizona, United States

  • Tgen Drug Development Services

    Scottsdale, Arizona, United States

  • St. Mary'S Medical Center

    San Francisco, California, United States

  • Indiana University Simon Cancer Center

    Indianapolis, Indiana, United States

  • Mayo Clinic Rochester

    Rochester, Minnesota, United States

  • Sarah Cannon Research Institute

    Nashville, Tennessee, United States

  • Mary Crowley Cancer Research Centers

    Dallas, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Evofosfamide
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
30 Jun 2007
Primary completion
31 Dec 2011
Completion
30 Jun 2012
Last update posted
27 Jul 2012
Registered enrollment
129
Registry id
NCT00495144

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.