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Clinical trialNCT00503997CompletedPhase 2Interventional

Pemetrexed and Oxaliplatin in Treating Patients With Locally Advanced Head and Neck Cancer

SponsorVanderbilt-Ingram Cancer CenterEnrollment42Head and Neck Cancer
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

RATIONALE: Pemetrexed may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as oxaliplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving pemetrexed together with oxaliplatin may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving pemetrexed together with oxaliplatin works in treating patients with locally advanced head and neck cancer.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

7 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Mitchell Memorial Cancer Center at Owensboro Medical Health System

    Owensboro, Kentucky, United States

  • Purchase Cancer Group - Paducah

    Paducah, Kentucky, United States

  • West Tennessee Cancer Center at Jackson-Madison County General Hospital

    Jackson, Tennessee, United States

  • Mbccop - Meharry Medical College - Nashville

    Nashville, Tennessee, United States

  • Vanderbilt-Ingram Cancer Center

    Nashville, Tennessee, United States

  • Vanderbilt-Ingram Cancer Center - Cool Springs

    Nashville, Tennessee, United States

  • Vanderbilt-Ingram Cancer Center at Franklin

    Nashville, Tennessee, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Oxaliplatin →Pemetrexed →
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 Dec 2006
Primary completion
30 Jun 2009
Completion
30 Jun 2010
Last update posted
10 May 2012
Registered enrollment
42
Registry id
NCT00503997
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.