Clinical trialNCT00514449CompletedPhase 2Interventional

Systematic Evaluation of Antiviral Medication in Schizophrenia

SponsorKonasale PrasadEnrollment31Schizoaffective DisorderSchizophrenia

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to examine whether antiviral medication will help improve psychotic symptoms and cognition in individuals early in the course of schizophrenia or schizoaffective disorder who are exposed to herpes simplex virus, type 1 (HSV 1), a virus that causes commonly occurring and recurrent cold sores.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Konasale Prasad, MD
Western Psychiatric Institute and Clinic
Principal Investigator
clinicaltrials.gov ↗
Matcheri Keshavan, MD
Wayne State University
Principal InvestigatorKOL profile →
clinicaltrials.gov ↗
Rajaprabhakaran Rajarethinam, MD
Wayne State University
Principal Investigator
clinicaltrials.gov ↗
Vishwajit Nimgaonkar, MD, PhD
Western Psychiatric Institute and Clinic
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

2 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Wayne State University
Detroit, Michigan, United States
Western Psychiatric Institute and Clinic
Pittsburgh, Pennsylvania, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

PlaceboValacyclovir →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 30 Jun 2007
Primary completion: 30 Sept 2016
Completion: 30 Sept 2016
Last update posted: 14 Jun 2018
Registered enrollment: 31
Registry id: NCT00514449

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.