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Clinical trialNCT00525824CompletedPhase 3Interventional

12-week Open-label, Phase IIIb Comparing Efficacy and Safety of Rosuvastatin (CRESTOR™) in Combination With Ezetimibe

SponsorAstraZenecaEnrollment1,743AtherosclerosisCoronary Heart DiseaseHypercholesterolemia
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to determine whether treatment of Rosuvastatin (CRESTOR™) or Simvastatin given as monotherapy or given in combination with Ezetimibe, will lower the Low Density Lipoprotein Cholesterol (LDL-C) in patients with Hypercholesterolaemia and Coronary Heart Disease (CHD) or a CHD Risk Equivalent, Atherosclerosis or a 10-year CHD Risk of \>20%
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

9 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Argentina
  • Research Site

    Buenos Aires, Argentina

Brazil
  • Research Site

    São Paulo, São Paulo, Brazil

Chile
  • Research Site

    Santiago, Chile

Colombia
  • Research Site

    Brentwood, Colombia

Lithuania
  • Research Site

    Brentwood, Lithuania

Netherlands
  • Research Site

    Zwinderen, Netherlands

Peru
  • Research Site

    Lima, San Isidro Lima, Peru

United States
  • Research Site

    Brentwood, Tennessee, United States

Venezuela
  • Research Site

    Brentwood, Venezuela

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Ezetimibe →Rosuvastatin →Simvastatin →
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 Aug 2007
Primary completion
30 Sept 2008
Completion
30 Sept 2008
Last update posted
13 May 2011
Registered enrollment
1,743
Registry id
NCT00525824
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.