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Clinical trialNCT00528489CompletedPhase 1Interventional

Safety and Effectiveness of PENNVAX-B Vaccine Alone, With Il-12, or IL-15 in Healthy Adults

SponsorNational Institute of Allergy and Infectious Diseases (NIAID)Enrollment120HIV Infections
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to determine the safety, tolerability, and immune response to the DNA HIV vaccine, PENNVAX-B alone, in combination with IL-12, or with 2 different doses of IL-15.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

8 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Alabama Vaccine Crs

    Birmingham, Alabama, United States

  • San Francisco Vaccine and Prevention Crs

    San Francisco, California, United States

  • Brigham and Women'S Hosp. Crs

    Boston, Massachusetts, United States

  • Hiv Prevention & Treatment Crs

    New York, New York, United States

  • Ny Blood Ctr./union Square Crs

    New York, New York, United States

  • Ny Blood Ctr./bronx Crs

    The Bronx, New York, United States

  • 3535 Market Street Crs

    Philadelphia, Pennsylvania, United States

  • Vanderbilt Vaccine Crs

    Nashville, Tennessee, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Interleukin-12 →IL-15PennVax B
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 Oct 2007
Primary completion
31 Jan 2010
Completion
31 Jan 2010
Last update posted
14 Oct 2021
Registered enrollment
120
Registry id
NCT00528489
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.