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Clinical trialNCT00550589CompletedPhase 2Interventional

Cidofovir in Treating HIV-Infected Patients With High-Grade Squamous Intraepithelial Lesions of the Skin Near the Anus

SponsorAIDS Malignancy ConsortiumEnrollment33Anal CancerPrecancerous Condition
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

RATIONALE: High-grade squamous intraepithelial lesions of the skin near the anus are caused by the human papillomavirus (HPV). Antiviral drugs,, such as cidofovir, act against viruses and may stop these lesions from becoming cancer. PURPOSE: This phase II trial is studying the side effects and how well topical cidofovir works in treating HIV-infected patients with high-grade squamous intraepithelial lesions of the skin near the anus.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

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Sites

8 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Ucla Clinical Aids Research and Education (care) Center

    Los Angeles, California, United States

  • Ucsf Helen Diller Family Comprehensive Cancer Center

    San Francisco, California, United States

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, United States

  • Boston University Cancer Research Center

    Boston, Massachusetts, United States

  • Laser Surgery Care

    New York, New York, United States

  • New York Weill Cornell Cancer Center at Cornell University

    New York, New York, United States

  • Montefiore Medical Center

    The Bronx, New York, United States

  • Benaroya Research Institute at Virginia Mason Medical Center

    Seattle, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
30 Sept 2007
Primary completion
28 Feb 2010
Completion
28 Feb 2010
Last update posted
21 Dec 2015
Registered enrollment
33
Registry id
NCT00550589

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.