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Clinical trialNCT00558922TerminatedPhase 1/PHASE2Interventional

A Phase 1-2 XIAP Antisense AEG35156 With Carboplatin and Paclitaxel in Patients With Advanced Non-Small Cell Lung Cancer

SponsorAegera TherapeuticsEnrollment54Carcinoma, Non-Small-Cell Lung
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is an open-label multicenter, phase 1-2 study. Following determination of the recommended AEG35156 dose in combination with carboplatin and paclitaxel in the initial Phase 1 part of this study, additional patients will be enrolled in the Phase 2 part of the study to assess the activity of the combination in advanced non small cell lung cancer.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

6 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Rocky Mountain Cancer Center

    Denver, Colorado, United States

  • Central Indiana Cancer Center

    Indianapolis, Indiana, United States

  • Dayton Oncology & Hematology, P.A.

    Dayton, Ohio, United States

  • Cancer Centers of the Carolinas

    Greenville, South Carolina, United States

  • Virginia Oncology Associates

    Norfolk, Virginia, United States

  • Northwest Cancer Specialists, P. C.

    Vancouver, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

AEG35156
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
30 Sept 2007
Primary completion
31 Aug 2009
Completion
31 Oct 2009
Last update posted
30 Jul 2009
Registered enrollment
54
Registry id
NCT00558922
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.