Clinical trialNCT00560859CompletedInterventional

Childhood Adenotonsillectomy Study for Children With OSAS

SponsorUniversity of PennsylvaniaEnrollment453Obstructive Sleep ApneaSnoring

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this research is to determine the effect of adenotonsillectomy surgery (removal of tonsils and adenoids) on obstructive sleep apnea syndrome (OSAS) in children. OSAS can cause health problems including poor growth, high blood pressure, diabetes and behavioral and learning difficulties. Although adenotonsillectomy is the usual treatment for children with OSAS, it is not known with any certainty if the child's OSAS symptoms improve afterwards. This study will help determine if improvement occurs or if it does not. It will also look at whether certain groups, such as children who are overweight or of different ethnicities, are helped by the surgery.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Bruno Giordani, PH.D.
Univeristy of Michigan
Study Director
clinicaltrials.gov ↗
Carol Rosen, MD
Case University School of Medicine; Rainbow Babies & Children's Hospital
Principal Investigator
clinicaltrials.gov ↗
Carole Marcus, MBB Ch.
Children's Hospital of Philadelphia
Principal Investigator
clinicaltrials.gov ↗
Eliot Katz, MD
Boston Children's Hospital, Boston MA
Principal Investigator
clinicaltrials.gov ↗
Hiren Muzumdar, MD
Montefiore Chilren's Hospital Albert Einstein Med Ctr, NY NY
Principal Investigator
clinicaltrials.gov ↗
Raanan Arens, MD
Montefiore Children's Hospital Albert Einstein Med Ctr, NY NY
Principal Investigator
clinicaltrials.gov ↗
Raouf Amin, MD
Cincinnati Children's Hopsital Medical Center (CCHMC)
Principal Investigator
clinicaltrials.gov ↗
Ron Chervin, MD, MS
University of Michigan
Principal Investigator
clinicaltrials.gov ↗
Ron Mitchell, MD
Cardinal Glennon Children's Medical Center, St. Louis MO
Principal Investigator
clinicaltrials.gov ↗
Susan Ellenberg, Ph.D.
University of Pennsylvania
Study Director
clinicaltrials.gov ↗
Susan Garetz, MD
University of Michigan
Study Director
clinicaltrials.gov ↗
Susan Redline, MD, MPH
Harvard University
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

6 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Children'S Hospital Boston
Boston, Massachusetts, United States
Cardinal Glennon Children'S Medical Center
St Louis, Missouri, United States
Montefiore Children'S Hospital
New York, New York, United States
Cincinnati Children'S Hospital Medical Center
Cincinnati, Ohio, United States
Rainbow Babies & Children'S Hospital
Cleveland, Ohio, United States
Children'S Hospital of Philadelphia
Philadelphia, Pennsylvania, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Oct 2007
Primary completion: 31 Mar 2012
Completion: 30 Jun 2012
Last update posted: 15 Dec 2015
Registered enrollment: 453
Registry id: NCT00560859

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.