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Clinical trialNCT00585559TerminatedPhase 3Interventional

Acetaminophen in aSAH to Inhibit Lipid Peroxidation and Cerebral Vasospasm

SponsorVanderbilt University Medical CenterEnrollment44Aneurysmal Subarachnoid HemorrhageCerebral Vasospasm
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The objective of this study is to determine whether acetaminophen (APAP), N-acetylcysteine (NAC), and APAP in combination with NAC will inhibit lipid peroxidation in aneurysmal subarachnoid hemorrhage (aSAH), utilizing F2-IsoPs as biomarkers for lipid peroxidation.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Vanderbilt University Medical Center

    Nashville, Tennessee, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

APAP 1 gm every 6 hours and N-acetylcysteine placeboAPAP 1 gm q6 hours, plus NAC IV infusion at 0.5 gm hourlyAPAP 1.5 gm q6 hours, plus NAC IV infusion at 0.5 gm hourlyNAC IV infusion at 0.5 gm hourly and APAP placeboPlacebos for acetaminophen and N-acetylcysteine
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
30 Apr 2007
Primary completion
26 Oct 2023
Completion
26 Oct 2023
Last update posted
18 Apr 2025
Registered enrollment
44
Registry id
NCT00585559
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.