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Clinical trialNCT00602420CompletedPhase 3Interventional

Prevention of Pegfilgrastim-Induced Bone Pain (PIBP)

SponsorGary MorrowEnrollment510Musculoskeletal ComplicationsPainUnspecified Adult Solid Tumor, Protocol Specific
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

RATIONALE: Naproxen may help prevent or lessen bone pain caused by pegfilgrastim. It is not yet known whether naproxen is more effective than a placebo in preventing bone pain caused by pegfilgrastim in patients with non-hematologic cancer undergoing chemotherapy. PURPOSE: This randomized phase III trial is studying naproxen to see how well it works compared with a placebo in preventing bone pain caused by pegfilgrastim in patients with non-hematologic cancer undergoing chemotherapy.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

16 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Mbccop - Hawaii

    Honolulu, Hawaii, United States

  • Ccop - Central Illinois

    Decatur, Illinois, United States

  • Ccop - Evanston

    Evanston, Illinois, United States

  • Ccop - Wichita

    Wichita, Kansas, United States

  • Ccop - Grand Rapids

    Grand Rapids, Michigan, United States

  • Ccop - Metro-Minnesota

    Saint Louis Park, Minnesota, United States

  • Ccop - Kansas City

    Kansas City, Missouri, United States

  • Ccop - Hematology-Oncology Associates of Central New York

    Syracuse, New York, United States

  • Ccop - Southeast Cancer Control Consortium

    Goldsboro, North Carolina, United States

  • Ccop - Columbus

    Columbus, Ohio, United States

  • Ccop - Dayton

    Dayton, Ohio, United States

  • Ccop - Greenville

    Greenville, South Carolina, United States

  • Ccop - Upstate Carolina

    Spartanburg, South Carolina, United States

  • Ccop - Virginia Mason Research Center

    Seattle, Washington, United States

  • Ccop - Northwest

    Tacoma, Washington, United States

  • Ccop - Marshfield Clinic Research Foundation

    Marshfield, Wisconsin, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Naproxen
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
30 Jun 2008
Primary completion
31 Jan 2012
Completion
31 Mar 2012
Last update posted
9 Nov 2015
Registered enrollment
510
Registry id
NCT00602420
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.