Clinical trialNCT00604175CompletedPhase 2Interventional

Safety of and Immune Response to the Human Papillomavirus (HPV) Vaccine in HIV-Infected Women

SponsorNational Institute of Allergy and Infectious Diseases (NIAID)Enrollment319HIV InfectionsSexually Transmitted Diseases

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Human papillomavirus (HPV) is the most common sexually transmitted disease in the world. HPV infection can cause genital warts and certain cervical problems, including cervical cancer. HPV infection may be more severe and harder to treat in HIV-infected people. The purpose of this study was to determine whether the quadrivalent HPV vaccine is safe, tolerable, and effective in producing antibodies to HPV in HIV-infected women.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Erna Milunka Kojic, MD
Department of Immunology/Infectious Disease, The Miriam Hospital, Brown University
Study Chair
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Susan Cu-Uvin, MD
Obstetrics-Gynecology and Medicine, The Miriam Hospital, Brown University
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

61 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Brazil

Instituto de Pesquisa Clinica Evandro Chagas (ipec) Crs
Rio de Janeiro, Brazil

Puerto Rico

Puerto Rico Aids Clinical Trials Unit Crs
San Juan, Puerto Rico
San Juan City Hosp. Pr Nichd Crs
San Juan, Puerto Rico
University of Puerto Rico Pediatric Hiv/aids Research Program Crs
San Juan, Puerto Rico

South Africa

Wits Helen Joseph Hospital Crs (wits Hjh Crs)
Johannesburg, Gauteng, South Africa

United States

Alabama Therapeutics Crs
Birmingham, Alabama, United States
Usc la Nichd Crs
Alhambra, California, United States
University of California, Uc San Diego Crs
La Jolla, California, United States
Miller Children'S Hosp. Long Beach Ca Nichd Crs
Long Beach, California, United States
Ucla Care Center Crs
Los Angeles, California, United States
University of Southern California Crs
Los Angeles, California, United States
Stanford Aids Clinical Trials Unit Crs
Palo Alto, California, United States
Ucsd Antiviral Research Center Crs
San Diego, California, United States
Ucsf Hiv/aids Crs
San Francisco, California, United States
University of Colorado Hospital Crs
Aurora, Colorado, United States
Denver Public Health Crs
Denver, Colorado, United States
Georgetown University Crs (gu Crs)
Washington D.C., District of Columbia, United States
Howard Univ. Washington Dc Nichd Crs
Washington D.C., District of Columbia, United States
South Florida Cdtc Ft Lauderdale Nichd Crs
Fort Lauderdale, Florida, United States
Univ. of Florida Jacksonville Nichd Crs
Jacksonville, Florida, United States
Pediatric Perinatal Hiv Clinical Trials Unit Crs
Miami, Florida, United States
the University of Miami Aids Clinical Research Unit (acru) Crs
Miami, Florida, United States
the Ponce de Leon Center Crs
Atlanta, Georgia, United States
Mt. Sinai Hosp. Med. Ctr. - Chicago, Womens & Childrens Hiv Program
Chicago, Illinois, United States
Northwestern University Crs
Chicago, Illinois, United States
Rush Univ. Med. Ctr. Actg Crs
Chicago, Illinois, United States
Rush University Crs
Chicago, Illinois, United States
Tulane Univ. New Orleans Nichd Crs
New Orleans, Louisiana, United States
Ihv Baltimore Treatment Crs
Baltimore, Maryland, United States
Johns Hopkins University Crs
Baltimore, Maryland, United States
Beth Israel Deaconess Med. Ctr., Actg Crs
Boston, Massachusetts, United States
Bmc Actg Crs
Boston, Massachusetts, United States
Massachusetts General Hospital Crs (mgh Crs)
Boston, Massachusetts, United States
Henry Ford Hosp. Crs
Detroit, Michigan, United States
Washington University Therapeutics (wt) Crs
St Louis, Missouri, United States
Cooper Univ. Hosp. Crs
Camden, New Jersey, United States
New Jersey Medical School- Adult Clinical Research Ctr. Crs
Newark, New Jersey, United States
Columbia Impaact Crs
New York, New York, United States
Columbia P&s Crs
New York, New York, United States
Ny Univ. Hiv/aids Crs
New York, New York, United States

21 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Quadrivalent HPV vaccine

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 29 Feb 2008
Primary completion: 31 Jan 2012
Completion: 30 Nov 2012
Last update posted: 4 Nov 2021
Registered enrollment: 319
Registry id: NCT00604175

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.