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Clinical trialNCT00622414CompletedPhase 1Interventional

Aflibercept in Treating Young Patients With Relapsed or Refractory Solid Tumors

SponsorNational Cancer Institute (NCI)Enrollment27Unspecified Childhood Solid Tumor, Protocol Specific
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This phase I trial is studying the side effects and best dose of aflibercept in treating young patients with relapsed or refractory solid tumors. Aflibercept may stop the growth of tumor cells by blocking blood flow to the tumor.

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

6 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Lurie Children'S Hospital-Chicago

    Chicago, Illinois, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, United States

  • Columbia University Medical Center

    New York, New York, United States

  • Oregon Health and Science University

    Portland, Oregon, United States

  • Baylor College of Medicine

    Houston, Texas, United States

  • Seattle Children'S Hospital

    Seattle, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
30 Apr 2008
Primary completion
28 Feb 2010
Completion
—
Last update posted
24 Feb 2014
Registered enrollment
27
Registry id
NCT00622414

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 4 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.