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Clinical trialNCT00632541TerminatedPhase 2Interventional

A Phase II Study of Bevacizumab + Sorafenib in Metastatic Breast Cancer

SponsorHoosier Cancer Research NetworkEnrollment18Metastatic Breast Cancer
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Prior clinical trials involving bevacizumab and sorafenib have demonstrated single agent activity in previously treated advanced breast cancer. This trial will test combined VEGF inhibition with sorafenib and bevacizumab in less heavily pre-treated patients with advanced breast cancer.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

10 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Medical & Surgical Specialists, Llc

    Galesburg, Illinois, United States

  • Oncology Hematology Associates of Sw Indiana

    Evansville, Indiana, United States

  • Fort Wayne Oncology & Hematology, Inc

    Fort Wayne, Indiana, United States

  • Indiana University Simon Cancer Center

    Indianapolis, Indiana, United States

  • Quality Cancer Center (mcgop)

    Indianapolis, Indiana, United States

  • Arnett Cancer Care

    Lafayette, Indiana, United States

  • Horizon Oncology Center

    Lafayette, Indiana, United States

  • Medical Consultants, P.C.

    Muncie, Indiana, United States

  • Northern Indiana Cancer Research Consortium

    South Bend, Indiana, United States

  • Ireland Cancer Center - University Hospitals of Cleveland

    Cleveland, Ohio, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Bevacizumab →Sorafenib →
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 Oct 2007
Primary completion
31 Mar 2009
Completion
31 Mar 2009
Last update posted
14 Feb 2018
Registered enrollment
18
Registry id
NCT00632541
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.