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Clinical trialNCT00659789CompletedPhase 2Interventional

Immunogenicity Study of Vacc-4x Versus Placebo in Patients Infected With HIV

SponsorBionor Immuno ASEnrollment137HIV I Infection
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Current management of HIV infection includes anti-retroviral therapy (ART). ART cannot cure the infection, making it a life-long treatment that requires sustained patient compliance and imposes significant individual and societal financial burdens on healthcare services. Furthermore, ART side effects often require medication that increases the inconveniences and financial burdens of HIV management. Of further concern is the emergence of viruses resistant to ART that can result in treatment failure. ART-free periods could provide substantial benefit. Vacc-4x is a peptide-based HIV immunotherapy that is proposed for prolongation of ART-free periods. The purpose of this study is to determine whether Vacc-4x immunotherapy can give safe ART-free period.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

18 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Germany
  • Charité Universitätsmedizin Berlin

    Berlin, State of Berlin, Germany

  • Epimed Gmbh

    Berlin, State of Berlin, Germany

  • Universitätsklinikum Bonn

    Bonn, Germany

  • Klinik I Für Innere Medizin Klinikum Der Universität Zu Köln

    Cologne, Germany

  • Universitätsklinikum Hamburg Eppendorf

    Hamburg, Germany

  • Ifi - Studien Und Projekte Gmbh, An Der Asklepios-Klinik St. George

    Hamburg, Germany

Italy
  • Istituto San Raffaele

    Milan, Italy

Spain
  • Hospital Germans Trias I Pujol

    Badalona, Spain

  • Hospital Clinic I Provincial

    Barcelona, Spain

  • Unidad de Vih, Hospital de Bellvitge, Calle Feixa Llarga S/n, Hospitalet de Llobregat.

    Barcelona, Spain

United Kingdom
  • Brighton and Sussex University Hospital, Hiv/gum Research, Elton John Centre

    Brighton, United Kingdom

  • Chelsea and Westminster Hospital

    London, United Kingdom

  • Harrison Wing St Thomas' Hospital

    London, United Kingdom

United States
  • Cedars-Sinai Medical Center

    Los Angeles, California, United States

  • Ucla Care Center

    Los Angeles, California, United States

  • Uc Davis Medical Center

    Sacramento, California, United States

  • University of Miami School of Medicine

    Miami, Florida, United States

  • Northwestern University Division of Infectious Diseases

    Chicago, Illinois, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Water →Vacc-4x
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 Aug 2008
Primary completion
30 Jun 2010
Completion
30 Jun 2011
Last update posted
23 Feb 2017
Registered enrollment
137
Registry id
NCT00659789

Cross-registrations

EU-CTR / CTIS (EudraCT)2007-006302-13
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.