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Clinical trialNCT00663234TerminatedPhase 1/PHASE2Interventional

IMPAACT P1063: Safety and Effectiveness of Atorvastatin in HIV Infected Children and Adolescents With Hyperlipidemia

SponsorInternational Maternal Pediatric Adolescent AIDS Clinical Trials GroupEnrollment28HIV InfectionsHyperlipidemia
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Treatment of HIV with combination antiretroviral regimens frequently results in the suppression of HIV viral load, significant immune recovery, and delayed disease progression. However, treatment with these regimens, particularly protease inhibitors (PIs), has been associated with significant increases in cholesterol and triglycerides in HIV-infected adults and children. The purpose of this study was to evaluate the safety and effectiveness of escalating doses of atorvastatin, a FDA-approved drug which lowers cholesterol and triglyceride levels, in HIV-infected children receiving stable antiretroviral regimens.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

11 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Univ. of Colorado Denver Nichd Crs (5052)

    Aurora, Colorado, United States

  • Univ. of Miami Ped. Perinatal Hiv/aids Crs (4201)

    Miami, Florida, United States

  • University of South Florida Tampa (5018)

    Tampa, Florida, United States

  • Chicago Children'S Crs (4001)

    Chicago, Illinois, United States

  • Tulane University (5095)

    New Orleans, Louisiana, United States

  • Boston Medical Center Ped. Hiv Program Nichd Crs (5011)

    Boston, Massachusetts, United States

  • Metropolitan Hospital (5003)

    New York, New York, United States

  • New York University Ny (5012)

    New York, New York, United States

  • Bronx-Lebanon Hospital Impaact Crs (6901)

    The Bronx, New York, United States

  • St. Jude/uthsc Crs (6501)

    Memphis, Tennessee, United States

  • Texas Children'S Hosp. Crs (3801)

    Houston, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Atorvastatin →
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 Aug 2009
Primary completion
31 Dec 2014
Completion
31 Dec 2014
Last update posted
6 Apr 2016
Registered enrollment
28
Registry id
NCT00663234
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.