Clinical trialNCT00668434CompletedPhase 2Interventional

Effectiveness of Oral Prednisone in Improving Physical Functioning and Decreasing Pain in People With Sciatica

SponsorKaiser PermanenteEnrollment269Sciatica

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Sciatica is a condition that causes a sharp, burning pain in the back, buttock, and leg. The condition is caused by injury to or compression of the sciatic nerve, which is located in the back of the leg. This study will determine the effectiveness of the steroid prednisone in decreasing pain and improving function in people with sciatica.

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Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Andrew L. Avins, MD, MPH
Kaiser Permanente Division of Research
Principal Investigator
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Harley Goldberg, DO
Kaiser Permanente San Jose Medical Center
Principal Investigator
clinicaltrials.gov ↗
Mark Tyburski, MD
Kaiser Permanente, Roseville
Principal Investigator
clinicaltrials.gov ↗
William Firtch, MD
Kaiser Permanente Redwood City
Principal Investigator
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A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

3 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Kaiser Permanente Northern California, Redwood City
Redwood City, California, United States
Kaiser Permanente
Roseville, California, United States
Kaiser Permanente Northern California, San Jose
San Jose, California, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

PlaceboPrednisone

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 30 Nov 2008
Primary completion: 30 Sept 2012
Completion: 30 Sept 2013
Last update posted: 28 Apr 2015
Registered enrollment: 269
Registry id: NCT00668434

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 4 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.