Clinical trialNCT00726622CompletedPhase 3Interventional

Laparoscopic-Assisted Resection or Open Resection in Treating Patients With Rectal Cancer

SponsorAlliance for Clinical Trials in OncologyEnrollment486Colorectal Cancer

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This study is being done to compare two types of surgery currently used for rectal cancer. The two types of surgery are laparoscopic-assisted rectal resection and open laparotomy rectal resection. Although laparoscopic-assisted rectal resection is being used for rectal cancer in some medical centers, the effectiveness of this type of surgery compared to open surgery is unknown. The study will compare the safety and effectiveness of the surgeries, recovery from surgery in the hospital, overall recovery from surgery and cancer outcome.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

James W. Fleshman, MD
Baylor Health
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

37 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada

St. Paul'S Hospital at Providence Health Care - Vancouver
Vancouver, British Columbia, Canada
St. Joseph'S Hospital - Charlton Campus
Hamilton, Ontario, Canada

United States

Mayo Clinic Scottsdale
Scottsdale, Arizona, United States
Cancer Care Center at John Muir Health - Concord Campus
Concord, California, United States
Kaiser Permanente Medical Center - Los Angeles
Los Angeles, California, United States
California Pacific Medical Center - California Campus
San Francisco, California, United States
John Muir/mt. Diablo Comprehensive Cancer Center
Walnut Creek, California, United States
Cleveland Clinic Florida - Weston
Weston, Florida, United States
John B. Amos Cancer Center
Columbus, Georgia, United States
Robert H. Lurie Comprehensive Cancer Center at Northwestern University
Chicago, Illinois, United States
Evanston Hospital
Evanston, Illinois, United States
Clarian North Medical Center
Carmel, Indiana, United States
Indiana University Melvin and Bren Simon Cancer Center
Indianapolis, Indiana, United States
Veterans Affairs Medical Center - Indianapolis
Indianapolis, Indiana, United States
William N. Wishard Memorial Hospital
Indianapolis, Indiana, United States
Kendrick Regional Center for Colon and Rectal Care - Mooresville
Mooresville, Indiana, United States
Holden Comprehensive Cancer Center at University of Iowa
Iowa City, Iowa, United States
Lahey Clinic Medical Center - Burlington
Burlington, Massachusetts, United States
Blodgett Hospital at Spectrum Health
Grand Rapids, Michigan, United States
Mayo Clinic Cancer Center
Rochester, Minnesota, United States
Boone Hospital Center
Columbia, Missouri, United States
Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis
St Louis, Missouri, United States
Overlook Hospital
Summit, New Jersey, United States
Memorial Sloan-Kettering Cancer Center
New York, New York, United States
Stony Brook University Cancer Center
Stony Brook, New York, United States
Suny Upstate Medical University Hospital
Syracuse, New York, United States
Duke Cancer Institute
Durham, North Carolina, United States
Cleveland Clinic Taussig Cancer Center
Cleveland, Ohio, United States
Integris Cancer Institute of Oklahoma - Proton Campus
Oklahoma City, Oklahoma, United States
Providence Cancer Center at Providence Portland Medical Center
Portland, Oregon, United States
Forbes Regional Hospital
Monroeville, Pennsylvania, United States
Allegheny Cancer Center at Allegheny General Hospital
Pittsburgh, Pennsylvania, United States
Western Pennsylvania Cancer Institute at Western Pennsylvania Hospital
Pittsburgh, Pennsylvania, United States
Lankenau Cancer Center at Lankenau Hospital
Wynnewood, Pennsylvania, United States
M. D. Anderson Cancer Center at University of Texas
Houston, Texas, United States
University of Wisconsin Paul P. Carbone Comprehensive Cancer Center
Madison, Wisconsin, United States
Medical College of Wisconsin Cancer Center
Milwaukee, Wisconsin, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Aug 2008
Primary completion: 31 Oct 2013
Completion: 1 Aug 2019
Last update posted: 7 May 2020
Registered enrollment: 486
Registry id: NCT00726622

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.