Clinical trialNCT00737763WithdrawnPhase 2Interventional

Beta Cell Rescue in New Onset Type 1 Diabetes With Efalizumab

SponsorEmory UniversityEnrollment0Diabetes Mellitus, Type 1

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

In this single-center therapeutic study, we will study the ability of efalizumab to protect remaining beta cells in teenagers and young adults who have been newly diagnosed with type 1 diabetes mellitus. Efalizumab is a monoclonal antibody which prevents the activation of antigen specific T lymphocytes to sites of inflammation. Efalizumab was approved by the FDA in 2003 for the treatment of psoriasis. It has been proven to be safe, well tolerated and effective in targeting T cell mediated disorders like those seen in autoimmunity.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Christian Larsen, MD, DPhil
Emory University
Principal Investigator
clinicaltrials.gov ↗
Eric Felner, MD
Children's Healthcare of Atlanta, Emory University
Principal Investigator
clinicaltrials.gov ↗
Mark R Rigby, MD, PhD
Emory University, Children's Healthcare of Atlanta
Principal Investigator
clinicaltrials.gov ↗
Sol Jacobs, MD
Emory University
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

No facility list is in our current data snapshot for this study. The registry record on ClinicalTrials.gov ↗ carries any published locations. Why? →

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

EfalizumabPlacebo

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Oct 2008
Primary completion: 30 Nov 2009
Completion: 30 Nov 2009
Last update posted: 12 May 2014
Registered enrollment: 0
Registry id: NCT00737763

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.