Clinical trialNCT00773890TerminatedPhase 1/PHASE2Interventional

TRF-1101 Assessment in Sickle Cell Disease

SponsorTRF Pharma, IncEnrollment80Sickle Cell Disease

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This study is designed to assess the safety, tolerability, and activity of TRF-1101 on microvascular blood flow, vascular endothelial injury, and vasoocclusive pain associated with sickle cell disease.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Stephen H Embury, M.D.
TRF Pharma, Inc
Study Director
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A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

6 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Howard University
Washington D.C., District of Columbia, United States
Medical College of Georgia
Augusta, Georgia, United States
University of Illinios Medical Center
Chicago, Illinois, United States
Boston Medical Center
Boston, Massachusetts, United States
Wayne State University Medical Center
Detroit, Michigan, United States
University of North Carolina
Chapel Hill, North Carolina, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

PlaceboTRF-1101

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Jul 2008
Primary completion: 31 May 2009
Completion: 31 May 2009
Last update posted: 11 May 2009
Registered enrollment: 80
Registry id: NCT00773890

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.