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Clinical trialNCT00809523CompletedPhase 2/PHASE3Interventional

A Trial of Negative Ion Generation Versus Light-Emitting Diode Phototherapy for Seasonal Affective Disorder (SAD)

SponsorYale UniversityEnrollment106Seasonal Affective Disorder
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is a randomized, controlled clinical trial of inactivated negative ion generation or light-emitting photodiode therapy for Seasonal Affective Disorder (SAD, winter depression), for subjects with a DSM IV diagnosis of Major Depression, with Seasonal Pattern, Winter type, to examine efficacy of treatments for this condition. The trial has a 1 week baseline phase and a 4 week treatment phase.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

8 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada
  • University of British Columbia

    Vancouver, British Columbia, Canada

  • St. John Regional Hospital

    Saint John, New Brunswick, Canada

  • Camh/university of Toronto

    Toronto, Ontario, Canada

  • Sleep and Alertness Inc

    Toronto, Ontario, Canada

Netherlands
  • University Medical Center Groningen

    Groningen, RB, Netherlands

United States
  • Yale University School of Medicine

    New Haven, Connecticut, United States

  • Capital Clinical Research Associates

    Rockville, Maryland, United States

  • Mclean Hospital/harvard

    Belmont, Massachusetts, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 Dec 2008
Primary completion
30 Apr 2010
Completion
30 Apr 2010
Last update posted
6 Mar 2013
Registered enrollment
106
Registry id
NCT00809523
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.