Clinical trialNCT00836329CompletedPhase 3Interventional

Improving Neurologic Outcomes in People With Diabetes Who Are Undergoing Heart Surgery

SponsorNational Heart, Lung, and Blood Institute (NHLBI)Enrollment133Cardiovascular DiseasesDiabetes Mellitus

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Preliminary studies have shown that people with diabetes who undergo heart surgery may have a higher risk of developing cognitive functioning problems, including memory problems, than people without diabetes who undergo heart surgery. Among people with diabetes, however, those who control their blood sugar levels in a more intensive way during and after heart surgery may have better neurological outcomes than those who use a standard method of controlling their blood sugar levels. This study will compare the effectiveness of using a traditional method of blood sugar control versus a more intensive method of blood sugar control during and after heart surgery for improving neurological outcomes in people with diabetes.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

David A. Stump, PhD
Wake Forest University Health Sciences
Study Director
clinicaltrials.gov ↗
Donald W. Bowden, PhD
Wake Forest University Health Sciences
Study Director
clinicaltrials.gov ↗
Edward H. Kincaid, MD
Wake Forest University Health Sciences
Principal Investigator
clinicaltrials.gov ↗
Jorge Calles-Escandon, MD
Wake Forest University Health Sciences
Study Director
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Wake Forest Baptist Medical Center
Winston-Salem, North Carolina, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Dec 2008
Primary completion: 31 May 2014
Completion: 31 May 2014
Last update posted: 12 Jul 2016
Registered enrollment: 133
Registry id: NCT00836329

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.