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Clinical trialNCT00863057TerminatedPhase 2Interventional

Combination Pain Therapy in HIV Neuropathy

SponsorNational Institute of Allergy and Infectious Diseases (NIAID)Enrollment15HIV InfectionsPeripheral Neuropathy
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Neuropathy results from damage to the nerves in the feet and legs. It is usually experienced as pain, tingling or numbness. In HIV-infected people, neuropathy can result from the infection itself or be a side effect of antiretroviral treatment. The purpose of this study is to determine whether two different drugs, methadone and duloxetine, reduce neuropathy-associated pain in HIV-infected people. This study will also examine whether utilization of both of these drugs is more effective than treatment with only one.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

8 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Ucsd, Avrc Crs

    San Diego, California, United States

  • Harbor-Ucla Med. Ctr. Crs

    Torrance, California, United States

  • University of Colorado Hospital Crs

    Aurora, Colorado, United States

  • Northwestern University Crs

    Chicago, Illinois, United States

  • Massachusetts General Hospital Actg Crs

    Boston, Massachusetts, United States

  • Washington U Crs

    St Louis, Missouri, United States

  • Metrohealth Crs

    Cleveland, Ohio, United States

  • Houston Aids Research Team Crs

    Houston, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Duloxetine →Duloxetine placeboMethadone →Methadone placebo
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 May 2009
Primary completion
31 Dec 2010
Completion
31 Dec 2010
Last update posted
4 Nov 2021
Registered enrollment
15
Registry id
NCT00863057
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.