Clinical trialNCT00873847CompletedObservational

Cerebral Function Monitoring in Premature Infants

SponsorNICHD Neonatal Research NetworkEnrollment102ElectroencephalographyInfant, Low Birth WeightInfant, NewbornInfant, PrematureInfant, Small for Gestational Age

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This observational study tests the feasibility of enrolling subjects and obtaining an amplitude-integrated electroencephalogram (aEEG) within the first 72 hours of life, a second aEEG recording between 72-168 hours of life, and weekly thereafter up to 36 weeks post-menstrual age. It will enroll 85-100 infants between 401-1,000 grams birth weight OR between 23 0/7 and 28 6/7 weeks gestational age born at the 7 participating NICHD Neonatal Research Network sites.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Abbot R. Laptook, MD
Brown University, Women & Infants Hospital of Rhode Island
Principal Investigator
clinicaltrials.gov ↗
Abhik Das, PhD
RTI International
Principal Investigator
clinicaltrials.gov ↗
Alexis Davis, MD
Stanford University
Principal Investigator
clinicaltrials.gov ↗
Barbara J. Stoll, MD
Emory University
Principal Investigator
clinicaltrials.gov ↗
Kathleen A. Kennedy, MD MPH
The University of Texas Health Science Center, Houston
Principal Investigator
clinicaltrials.gov ↗
Lina Chalak, MD
University of Texas, Southwestern Medical Center at Dallas
Principal Investigator
clinicaltrials.gov ↗
Ricki F. Goldstein, MD
Duke University
Principal Investigator
clinicaltrials.gov ↗
Seetha Shankaran, MD
Wayne State University
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

8 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Stanford University
Palo Alto, California, United States
Emory University
Atlanta, Georgia, United States
Wayne State University
Detroit, Michigan, United States
Duke University
Durham, North Carolina, United States
Rti International
Durham, North Carolina, United States
Brown University, Women & Infants Hospital of Rhode Island
Providence, Rhode Island, United States
University of Texas Southwestern Medical Center at Dallas
Dallas, Texas, United States
University of Texas Health Science Center at Houston
Houston, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Jul 2009
Primary completion: 30 Jun 2010
Completion: 31 Aug 2012
Last update posted: 26 Sept 2017
Registered enrollment: 102
Registry id: NCT00873847

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 4 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.