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Clinical trialNCT00880087CompletedInterventional

Therapeutic Hypothermia to Improve Survival After Cardiac Arrest in Pediatric Patients-THAPCA-IH [In Hospital] Trial

SponsorUniversity of MichiganEnrollment329Cardiac Arrest
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Cardiac arrest is a sudden, unexpected loss of heart function. Therapeutic hypothermia, in which the body's temperature is lowered and maintained several degrees below normal for a period of time, has been used to successfully treat adults who have experienced cardiac arrest. This study will evaluate the efficacy of therapeutic hypothermia at increasing survival rates and reducing the risk of brain injury in infants and children who experience a cardiac arrest while in the hospital.

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

33 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada
  • the Hospital for Sick Children

    Toronto, Ontario, Canada

United Kingdom
  • Birmingham Children'S Hospital

    Birmingham, United Kingdom

  • Bristol Royal Hospital for Children

    Bristol, United Kingdom

  • University of Hampton

    Hampton, United Kingdom

  • Alder Hey Children'S Hospital

    Liverpool, United Kingdom

  • Evalina Children'S at Guys'S and St. Thomas' Hospital

    London, United Kingdom

  • Great Ormand Street Hospital

    London, United Kingdom

  • Royal Manchester Children'S Hospital

    Manchester, United Kingdom

United States
  • the Children'S Hospital of Alabama

    Birmingham, Alabama, United States

  • Phoenix Children'S Hospital

    Phoenix, Arizona, United States

  • Loma Linda University Children'S Hospital

    Loma Linda, California, United States

  • Children'S Hospital of Los Angeles

    Los Angeles, California, United States

  • University of California, Los Angeles

    Los Angeles, California, United States

  • Children'S Hospital of Orange County

    Orange, California, United States

  • University of California San Francisco

    San Francisco, California, United States

  • Children'S National Medical Center

    Washington D.C., District of Columbia, United States

  • Children'S Hospital of Atlanta/emory University

    Atlanta, Georgia, United States

  • Riley Children'S Hospital

    Indianapolis, Indiana, United States

  • Kosair Children'S Hospital

    Louisville, Kentucky, United States

  • Johns Hopkins Hospital

    Baltimore, Maryland, United States

  • University of Michigan, Mott Children'S Hospital

    Ann Arbor, Michigan, United States

  • Children'S Hospital of Michigan

    Detroit, Michigan, United States

  • Washington University in St. Louis

    St Louis, Missouri, United States

  • Duke Children'S Hospital

    Durham, North Carolina, United States

  • Nationwide Children'S Hospital in Columbus

    Columbus, Ohio, United States

  • Penn State Children'S Hospital

    Hershey, Pennsylvania, United States

  • Children'S Hospital of Philidelphia

    Philadelphia, Pennsylvania, United States

  • University of Pittsburgh

    Pittsburgh, Pennsylvania, United States

  • Lebonheur Children'S Hospital - University of Tennessee at Memphis

    Memphis, Tennessee, United States

  • Children'S Medical Center Dallas

    Dallas, Texas, United States

  • University of Texas Health Sciences Center of San Antonio

    San Antonio, Texas, United States

  • Primary Children'S Medical Center

    Salt Lake City, Utah, United States

  • Seattle Children'S Hospital

    Seattle, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
30 Sept 2009
Primary completion
29 Feb 2016
Completion
29 Feb 2016
Last update posted
15 Jun 2018
Registered enrollment
329
Registry id
NCT00880087

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 4 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.