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Clinical trialNCT00888173CompletedPhase 2Interventional

Brivanib Alaninate in Treating Patients With Recurrent or Persistent Endometrial Cancer

SponsorGynecologic Oncology GroupEnrollment45Endometrial AdenocarcinomaEndometrial Clear Cell AdenocarcinomaEndometrial Mixed AdenocarcinomaEndometrial Mucinous AdenocarcinomaEndometrial Serous AdenocarcinomaEndometrial Squamous Cell Carcinoma+3 more conditions
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This phase II trial is studying how well brivanib alaninate works in treating patients with endometrial cancer that has come back (recurred) or is persistent. Brivanib alaninate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

35 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • University of Colorado Cancer Center - Anschutz Cancer Pavilion

    Aurora, Colorado, United States

  • the Hospital of Central Connecticut

    New Britain, Connecticut, United States

  • Rush University Medical Center

    Chicago, Illinois, United States

  • Saint Vincent Hospital and Health Care Center

    Indianapolis, Indiana, United States

  • Mcfarland Clinic Pc-William R Bliss Cancer Center

    Ames, Iowa, United States

  • Iowa Lutheran Hospital

    Des Moines, Iowa, United States

  • Iowa Methodist Medical Center

    Des Moines, Iowa, United States

  • Iowa-Wide Oncology Research Coalition Ncorp

    Des Moines, Iowa, United States

  • Medical Oncology and Hematology Associates-Des Moines

    Des Moines, Iowa, United States

  • Medical Oncology and Hematology Associates-Laurel

    Des Moines, Iowa, United States

  • Mercy Medical Center - Des Moines

    Des Moines, Iowa, United States

  • University of Iowa/holden Comprehensive Cancer Center

    Iowa City, Iowa, United States

  • Spectrum Health at Butterworth Campus

    Grand Rapids, Michigan, United States

  • Washington University School of Medicine

    St Louis, Missouri, United States

  • Nebraska Methodist Hospital

    Omaha, Nebraska, United States

  • North Shore University Hospital

    Manhasset, New York, United States

  • Long Island Jewish Medical Center

    New Hyde Park, New York, United States

  • North Shore-Lij Health System/center for Advanced Medicine

    New Hyde Park, New York, United States

  • Duke University Medical Center

    Durham, North Carolina, United States

  • Metrohealth Medical Center

    Cleveland, Ohio, United States

  • University of Oklahoma Health Sciences Center

    Oklahoma City, Oklahoma, United States

  • Oklahoma Cancer Specialists and Research Institute-Tulsa

    Tulsa, Oklahoma, United States

  • Abington Memorial Hospital

    Abington, Pennsylvania, United States

  • Huntsman Cancer Institute/university of Utah

    Salt Lake City, Utah, United States

  • Carilion Clinic Gynecological Oncology

    Roanoke, Virginia, United States

  • Fred Hutchinson Cancer Research Center

    Seattle, Washington, United States

  • Northwest Hospital

    Seattle, Washington, United States

  • Pacific Gynecology Specialists

    Seattle, Washington, United States

  • Seattle Cancer Care Alliance

    Seattle, Washington, United States

  • Swedish Medical Center-First Hill

    Seattle, Washington, United States

  • University of Washington Medical Center

    Seattle, Washington, United States

  • Green Bay Oncology Limited at Saint Mary'S Hospital

    Green Bay, Wisconsin, United States

  • Green Bay Oncology at Saint Vincent Hospital

    Green Bay, Wisconsin, United States

  • Saint Vincent Hospital Cancer Center Green Bay

    Green Bay, Wisconsin, United States

  • Gundersen Lutheran Medical Center

    La Crosse, Wisconsin, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Brivanib alaninate
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
6 Jul 2009
Primary completion
16 Jul 2016
Completion
16 Jul 2016
Last update posted
6 Dec 2017
Registered enrollment
45
Registry id
NCT00888173

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.