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Clinical trialNCT00911508CompletedInterventional

Catheter Ablation vs Anti-arrhythmic Drug Therapy for Atrial Fibrillation Trial

SponsorMayo ClinicEnrollment2,204ArrhythmiaAtrial Fibrillation
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The (Catheter Ablation Versus Anti-arrhythmic Drug Therapy for Atrial Fibrillation Trial) CABANA Trial has the overall goal of establishing the appropriate roles for medical and ablative intervention for atrial fibrillation (AF). The CABANA Trial is designed to test the hypothesis that the treatment strategy of left atrial catheter ablation for the purpose of eliminating atrial fibrillation (AF) will be superior to current state-of-the-art therapy with either rate control or rhythm control drugs for decreasing the incidence of the composite endpoint of total mortality, disabling stroke, serious bleeding, or cardiac arrest in patients with untreated or incompletely treated AF.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

118 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Australia
  • Royal Adelaide Hospital

    Adelaide, South Australia, Australia

  • Royal Melbourne Hospital

    Parkville, Victoria, Australia

Canada
  • University of Calgary

    Calgary, Alberta, Canada

  • Hamilton Health Sciences

    Hamilton, Ontario, Canada

  • University of Western Ontario - London Health Sciences Centre

    London, Ontario, Canada

  • Southlake Regional Health Centre

    Newmarket, Ontario, Canada

China
  • Guangdong Provincial People'S Hospital

    Guangzhou, Guangdong, China

  • First Affiliated Hospital of Nanjing Medical University

    Nanjing, Jiangsu, China

  • First Affiliated Hospital of Dalian Medical University

    Dalian, Liaoning, China

  • Beijing Anzhen Hospital

    Beijing, China

  • Fuwai Hospital

    Beijing, China

Czechia
  • Na Homolce Hospital

    Prague, Prague, Czechia

  • Saint Anne'S University Hospital, Icrc

    Brno, Czechia

  • Charles University

    Prague, Czechia

  • Clinic of Cardiology Ikem Medical Institute

    Prague, Czechia

Germany
  • University Hospital of Mannheim

    Mannheim, Baden-Wurttemberg, Germany

  • Klinikum Coburg

    Coburg, Bavaria, Germany

  • Universitares Herrzentrum Hamburg

    Hamburg, Freie-Hansestadt Hamburg, Germany

  • Herz-Und Diabeteszentrum Nrw

    Bad Oeynhausen, North Rhine-Westphalia, Germany

  • Technische Universitat Dresden

    Dresden, Saxony, Germany

  • Kerckhoff Klinik

    Bad Nauheim, Germany

  • Praxisklinik Herz and Gefabe

    Dresden, Germany

  • Ccb - Cardioaniologisches Centrum Bethanien

    Frankfurt, Germany

  • Georg-August-University

    Göttingen, Germany

  • Asklepios Klinik Barmbek

    Hamburg, Germany

  • Asklepios Klinik St. Georg

    Hamburg, Germany

  • Saint Vincentius-Kliniken

    Karlsruhe, Germany

  • Herzzentrum Leipzig

    Leipzig, Germany

  • Universitat Rostock

    Rostock, Germany

Italy
  • Policlinico San Donato Center of Clinical Arrhythmia and Electrophysiology

    San Donato Milanese, Lombardy, Italy

  • Policlinico Multimedical Cardiology and Arrhythmia Centre

    Milan, Italy

  • Ospedale Di Circolo E Fondazione Macchi

    Varese, Italy

Russia
  • Research Institute of Circulation of Pathology

    Novosibirsk, Novosibirsk Oblast, Russia

  • Bakoulev Scientific Center for Cardiovascular Surgery

    Moscow, Russia

  • Clinical Hospital # 83 Under the Federal Medical and Biological Agency

    Moscow, Russia

  • Scientific Research Institute of Cardiology of Ministry of Health of Russian Foundation

    Tomsk, Russia

South Korea
  • Korea University Anam Hospital

    Seoul, South Korea

  • Yonsei University Severance Hospital

    Seoul, South Korea

United Kingdom
  • Golden Jubilee Hospital

    Glasgow, United Kingdom

  • Saint Bartholomew'S Hospital

    London, United Kingdom

78 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Rate or Rhythm Control Therapy
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
13 Nov 2009
Primary completion
31 Dec 2017
Completion
31 Dec 2017
Last update posted
21 Apr 2021
Registered enrollment
2,204
Registry id
NCT00911508

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.