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Clinical trialNCT00920699CompletedPhase 2Interventional

Study in PRE-manifest Huntington's Disease of Coenzyme Q10 (UbiquinonE) Leading to Preventive Trials (PREQUEL)

SponsorJohns Hopkins UniversityEnrollment90Huntington's Disease
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

To establish the tolerability of treatment with 600, 1200 or 2400 mg per day of coenzyme Q10 in pre-manifest participants carrying the CAGn expansion for Huntington's Disease (HD).
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

13 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • University of California Davis

    Sacramento, California, United States

  • Colorado Neurological Institute

    Englewood, Colorado, United States

  • University of Miami School of Medicine

    Miami, Florida, United States

  • Emory University School of Medicine

    Atlanta, Georgia, United States

  • Indiana University School of Medicine

    Indianapolis, Indiana, United States

  • University of Iowa

    Iowa City, Iowa, United States

  • Hereditary Neurological Disease Centre (hndc)

    Wichita, Kansas, United States

  • Johns Hopkins University

    Baltimore, Maryland, United States

  • Hennepin County Medical Center

    Minneapolis, Minnesota, United States

  • Washington University

    St Louis, Missouri, United States

  • Albany Medical College

    Albany, New York, United States

  • University of Rochester

    Rochester, New York, United States

  • Baylor College of Medicine

    Houston, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Ubidecarenone
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
28 Feb 2010
Primary completion
31 Mar 2012
Completion
31 Mar 2012
Last update posted
25 Sept 2017
Registered enrollment
90
Registry id
NCT00920699
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.