Clinical trialNCT00927784TerminatedPhase 2Interventional

Effect of Intramyocardial Injection of Mesenchymal Precursor Cells on Heart Function in People Receiving an LVAD

SponsorIcahn School of Medicine at Mount SinaiEnrollment10Heart Failure

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Left ventricular assist devices (LVADs) are one treatment option for people with congestive heart failure. This study will evaluate the safety of injecting mesenchymal precursor cells (MPCs) into the heart during LVAD implantation surgery and examine if injecting MPCs into the heart is effective at improving heart function.

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Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Deborah Ascheim, MD
Icahn School of Medicine at Mount Sinai
Principal Investigator
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Yoshifumi Naka, MD
Columbia University
Principal Investigator
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A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

17 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Sharp Memorial Hospital
San Diego, California, United States
Washington Hospital Center
Washington D.C., District of Columbia, United States
Advocate Christ Medical Center
Oak Lawn, Illinois, United States
Jewish Hospital
Louisville, Kentucky, United States
University of Michigan
Ann Arbor, Michigan, United States
University of Minnesota
Minneapolis, Minnesota, United States
Mayo Clinic
Rochester, Minnesota, United States
Columbia University Medical Center
New York, New York, United States
Mount Sinai Medical Center
New York, New York, United States
Montefiore Medical Center
The Bronx, New York, United States
Ohio State University Medical Center
Columbus, Ohio, United States
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania, United States
Temple University Hospital
Philadelphia, Pennsylvania, United States
Intermountain Medical Center
Salt Lake City, Utah, United States
Sacred Heart Medical Center
Spokane, Washington, United States
University of Wisconsin
Madison, Wisconsin, United States
St. Luke'S Medical Center
Milwaukee, Wisconsin, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Cryoprotective media aloneMesenchymal Precursor cells

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Aug 2009
Primary completion: 31 May 2010
Completion: 28 Feb 2011
Last update posted: 5 Mar 2019
Registered enrollment: 10
Registry id: NCT00927784

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Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.