Clinical trialNCT00940823CompletedInterventional

The AVB Study: Prospective Study Comparing the Ahmed Valve and the Baerveldt Implant for Treating Refractory Glaucoma

SponsorCredit Valley EyeCareEnrollment238Glaucoma

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to compare the safety and efficacy of the Ahmed valve and the Baerveldt implant in treating refractory glaucoma. Eligible patients will be recruited from multiple study centers and randomized to a glaucoma drainage device for implantation. They will be followed long-term based upon outcome measures including intraocular pressure, glaucoma medication use, visual acuity, complications of the surgery and further treatments required.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Iqbal K Ahmed, MD
University of Toronto Department of Ophthalmology & Vision Sciences
Study Chair
clinicaltrials.gov ↗
James C Tsai, MD
Yale Ophthalmology & Visual Science
Principal Investigator
clinicaltrials.gov ↗
Jeffrey A Kammer, MD
Department of Ophthalmology and Visual Sciences: Vanderbilt University, School of Medicine
Principal Investigator
clinicaltrials.gov ↗
Jeffrey W Kalenak, MD
Drs. Massaro & Kalenak, SC
Principal Investigator
clinicaltrials.gov ↗
Juan J Mura, MD
Clinic of Las Condes
Principal Investigator
clinicaltrials.gov ↗
Louis B Cantor, MD
Department of Ophthalmology, Indiana University
Principal Investigator
clinicaltrials.gov ↗
Panos G Christakis, BS
Yale University
Study Director
clinicaltrials.gov ↗
Paul J Harasymowycz, MD
University of Montreal: Department of Ophthalmology
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

6 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada

Credit Valleyec
Toronto, Ontario, Canada
Montreal Glaucoma Institute
Montreal, Quebec, Canada

Chile

Clinic of Las Condes
Santiago, Chile

United States

Eugene and Marilyn Glick Eye Institute
Indianapolis, Indiana, United States
Vanderbilt Eye Institute
Nashville, Tennessee, United States
Drs. Massaro and Kalenak
Milwaukee, Wisconsin, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Jul 2005
Primary completion: 30 Apr 2014
Completion: 30 Apr 2015
Last update posted: 13 Mar 2018
Registered enrollment: 238
Registry id: NCT00940823

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.