Clinical trialNCT00977756CompletedObservational

IMPAACT P1058A: Pharmacokinetic Effects of New Antiretroviral Drugs on Children, Adolescents and Young Adults

SponsorInternational Maternal Pediatric Adolescent AIDS Clinical Trials GroupEnrollment168HIV Infections

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This study will examine drug and body interactions in children receiving anti-HIV treatment regimens using new medications. Drug regimens to be examined will feature the medications raltegravir (RAL), maraviroc (MVC), and etravirine (ETV). These drugs will not be provided through the study.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Jennifer R. King, PharmD
University of Alabama at Birmingham
Study Chair
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Ram Yogev, MD
Northwestern University
Study ChairKOL profile →
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A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

35 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Puerto Rico

San Juan City Hosp. Pr Nichd Crs (5031)
San Juan, Puerto Rico
University of Puerto Rico Pediatric Hiv/aids Research (6601)
San Juan, Puerto Rico

United States

Univ. of Alabama Birmingham Nichd Crs (5096)
Birmingham, Alabama, United States
Miller Children'S Hospital Long Beach, Ca Nichd Crs (5093)
Long Beach, California, United States
Usc la Nichd Crs (5048)
Los Angeles, California, United States
Ucsd Mother, Child & Adolescent Hiv Program(4601)
San Diego, California, United States
Univ. of California San Francisco Nichd Crs (5091)
San Francisco, California, United States
Harbor (ucla) Medical Center Nichd Crs (5045)
Torrance, California, United States
Harbor Univeristy of California, Los Angeles (ucla) Medical Center (603)
Torrance, California, United States
Childrens Hospital (u. Colorado, Denver) Nichd Crs (5052)
Denver, Colorado, United States
Children'S National Medical Center (5015)
Washington D.C., District of Columbia, United States
South Florida Cdc Ft Lauderdale Nichd Crs (5055)
Fort Lauderdale, Florida, United States
University of Miami Pediatric Perinatal Hiv/aids Crs (4201)
Miami, Florida, United States
University of South Florida Tampa (5018)
Tampa, Florida, United States
Chicago Children'S Crs (4001)
Chicago, Illinois, United States
Rush University Cook County (5083)
Chicago, Illinois, United States
Johns Hopkins University Nichd Crs (5092)
Baltimore, Maryland, United States
University of Maryland Nichd Crs (5094)
Baltimore, Maryland, United States
Boston Medical Center Ped. Hiv Program Nichd Crs (5011)
Boston, Massachusetts, United States
Children'S Hospital of Boston Nichd Crs (5009)
Boston, Massachusetts, United States
Wne Maternal Pediatric Adolescent Aids Crs (7301)
Worcester, Massachusetts, United States
New Jersey Medical School (nj) (2802)
Newark, New Jersey, United States
Columbia Impaact Crs (4101)
New York, New York, United States
Metropolitan Hospital (5003)
New York, New York, United States
New York University Ny (5012)
New York, New York, United States
Suny Stony Brook Nichd Crs (5040)
Stony Brook, New York, United States
Bronx-Lebanon Hospital (6901)
The Bronx, New York, United States
Jacobi Medical Center Bronx (5013)
The Bronx, New York, United States
Duke University Medical Center (dumc) (4701)
Durham, North Carolina, United States
the Children'S Hosp. of Philadelphia Impaact Crs (6701)
Philadelphia, Pennsylvania, United States
St. Jude/uthsc Crs (6501)
Memphis, Tennessee, United States
Texas Children'S Hosp. Crs (3801)
Houston, Texas, United States
Harborview Medical Center Nichd Crs (5027)
Seattle, Washington, United States
Univ of Washington Children'S Hospital Seattle (5017)
Seattle, Washington, United States
University of Washington Nichd Crs (5029)
Seattle, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Atazanavir →Darunavir →Etravirine →Lopinavir →Maraviroc →Raltegravir →Ritonavir →Tenofovir

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Aug 2002
Primary completion: 31 Mar 2014
Completion: 31 Mar 2014
Last update posted: 7 Aug 2015
Registered enrollment: 168
Registry id: NCT00977756

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.