Clinical trialNCT00998192CompletedPhase 2Interventional

A Study of REOLYSIN® in Combination With Paclitaxel and Carboplatin in Patients With Squamous Cell Carcinoma of the Lung

SponsorOncolytics BiotechEnrollment32Metastatic or Recurrent Squamous Cell Carcinoma of the Lung

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this Phase 2 study is to investigate whether intravenous administration of REOLYSIN therapeutic reovirus in combination with paclitaxel and carboplatin is effective and safe in the treatment of squamous cell carinoma of the lung.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Alain Mita, MD
Cedars-Sinai Medical Center
Principal Investigator
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A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

17 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Cedars-Sinai Medical Center
Los Angeles, California, United States
Ocala Oncology Center
Ocala, Florida, United States
Illinois Cancer Specialists
Niles, Illinois, United States
Investigative Clinical Research of Indiana, Llc
Indianapolis, Indiana, United States
Advanced Oncology Associates
Armonk, New York, United States
Signal Point Clinical Research Center, Llc
Middletown, Ohio, United States
Medical Oncology Associates of Wyoming Valley
Kingston, Pennsylvania, United States
Texas Oncology - Arlington South
Arlington, Texas, United States
Texas Oncology - Bedford
Bedford, Texas, United States
Texas Oncology - Denton South
Denton, Texas, United States
Texas Oncology - Fort Worth
Fort Worth, Texas, United States
Texas Oncology - Garland
Garland, Texas, United States
Texas Oncology - Lewisville
Lewisville, Texas, United States
Cancer Care Centers of South Texas
San Antonio, Texas, United States
Cancer Therapy & Research Center at Uthscsa
San Antonio, Texas, United States
Texas Oncology - Tyler
Tyler, Texas, United States
Lynchburg Hematology Oncology Clinic
Lynchburg, Virginia, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Carboplatin →Paclitaxel →REOLYSIN

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Oct 2009
Primary completion: 30 Sept 2013
Completion: 31 Aug 2015
Last update posted: 31 Mar 2016
Registered enrollment: 32
Registry id: NCT00998192

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.