Clinical trialNCT01013610CompletedPhase 1Interventional

An Escalating Dose Study to Evaluate the Safety, Tolerability and Pharmacokinetics of LNK 754 in Elderly Volunteers and in Subjects With Mild Alzheimer's Disease

SponsorLink Medicine CorporationEnrollment110Mild Alzheimer's Disease

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

To evaluate the safety, tolerability, multiple dose plasma pharmacokinetics (PK) of LNK-754 in male and female elderly volunteers after dosing with LNK-754 for 7 days and in subjects with mild Alzheimer's Disease after dosing with LNK-754 for 28 days.

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Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Abel Murillo, MD
Elite Research Institute
Principal Investigator
clinicaltrials.gov ↗
Armen Goenjian, MD
Collaborative Neuroscience Network
Principal Investigator
clinicaltrials.gov ↗
Craig T. Curtis, MD
Compass Research
Principal Investigator
clinicaltrials.gov ↗
Kyle Patrick, D.O.
Dedicated Phase I
Principal Investigator
clinicaltrials.gov ↗
Maxwell Axler, MD
Clinical Trial Network
Principal Investigator
clinicaltrials.gov ↗
Ricky S. Mofsen, D.O.
St. Louis Clinical Trials, LC
Principal Investigator
clinicaltrials.gov ↗
Robert Riesenberg, MD
Atlanta Center for Medical Research
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

7 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Dedicated Phase I
Phoenix, Arizona, United States
Collaborative Neuroscience Network
Long Beach, California, United States
Elite Research Insitute
Miami, Florida, United States
Compass Research, Llc
Orlando, Florida, United States
Atlanta Center for Medical Research
Atlanta, Georgia, United States
St. Louis Clinical Trials, Lc
St Louis, Missouri, United States
Clinical Trial Network
Houston, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

LNK-754Placebo

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 30 Nov 2009
Primary completion: 31 Mar 2011
Completion: 31 Mar 2011
Last update posted: 15 Mar 2011
Registered enrollment: 110
Registry id: NCT01013610

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.