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Clinical trialNCT01017601TerminatedPhase 2Interventional

Seneca Valley Virus-001 After Chemotherapy in Treating Patients With Extensive-Stage Small Cell Lung Cancer

SponsorAlliance for Clinical Trials in OncologyEnrollment59Lung Cancer
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

RATIONALE: A virus called Seneca Valley virus-001 (NTX-010) may be able to kill tumor cells without damaging normal cells. It is not yet known whether NTX-010 is more effective than a placebo in treating small cell lung cancer. PURPOSE: This randomized phase II trial is studying NTX-010 to see how well it works compared with a placebo when given after chemotherapy in treating patients with extensive-stage small cell lung cancer.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

196 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Mayo Clinic Scottsdale

    Scottsdale, Arizona, United States

  • Arkansas Cancer Research Center at University of Arkansas for Medical Sciences

    Little Rock, Arkansas, United States

  • East Bay Radiation Oncology Center

    Castro Valley, California, United States

  • Valley Medical Oncology Consultants - Castro Valley

    Castro Valley, California, United States

  • Valley Medical Oncology

    Fremont, California, United States

  • Contra Costa Regional Medical Center

    Martinez, California, United States

  • El Camino Hospital Cancer Center

    Mountain View, California, United States

  • Alta Bates Summit Medical Center - Summit Campus

    Oakland, California, United States

  • Bay Area Breast Surgeons, Incorporated

    Oakland, California, United States

  • Ccop - Bay Area Tumor Institute

    Oakland, California, United States

  • Epic Care - Oakland

    Oakland, California, United States

  • Highland General Hospital

    Oakland, California, United States

  • Larry G Strieff Md Medical Corporation

    Oakland, California, United States

  • Tom K Lee, Incorporated

    Oakland, California, United States

  • Doctors Medical Center - San Pablo Campus

    San Pablo, California, United States

  • Saint Francis/mount Sinai Regional Cancer Center at Saint Francis Hospital and Medical Center

    Hartford, Connecticut, United States

  • George Bray Cancer Center at the Hospital of Central Connecticut - New Britain Campus

    New Britain, Connecticut, United States

  • Mayo Clinic - Jacksonville

    Jacksonville, Florida, United States

  • Saint Alphonsus Cancer Care Center at Saint Alphonsus Regional Medical Center

    Boise, Idaho, United States

  • St. Joseph Regional Medical Center

    Lewiston, Idaho, United States

  • Ccop - Carle Cancer Center

    Urbana, Illinois, United States

  • Elkhart Clinic, Llc

    Elkhart, Indiana, United States

  • Elkhart General Hospital

    Elkhart, Indiana, United States

  • Michiana Hematology-Oncology, Pc - Elkhart

    Elkhart, Indiana, United States

  • Fort Wayne Medical Oncology and Hematology

    Fort Wayne, Indiana, United States

  • Howard Community Hospital

    Kokomo, Indiana, United States

  • Center for Cancer Therapy at Laporte Hospital and Health Services

    La Porte, Indiana, United States

  • Saint Anthony Memorial Health Centers

    Michigan City, Indiana, United States

  • Michiana Hematology-Oncology, Pc - South Bend

    Mishawaka, Indiana, United States

  • Saint Joseph Regional Medical Center

    Mishawaka, Indiana, United States

  • Michiana Hematology Oncology Pc - Plymouth

    Plymouth, Indiana, United States

  • Ccop - Northern Indiana Cr Consortium

    South Bend, Indiana, United States

  • Memorial Hospital of South Bend

    South Bend, Indiana, United States

  • Michiana Hematology Oncology Pc - la Porte

    Westville, Indiana, United States

  • Cedar Rapids Oncology Associates

    Cedar Rapids, Iowa, United States

  • Mercy Regional Cancer Center at Mercy Medical Center

    Cedar Rapids, Iowa, United States

  • Medical Oncology and Hematology Associates - West Des Moines

    Clive, Iowa, United States

  • Mercy Cancer Center - West Lakes

    Clive, Iowa, United States

  • Ccop - Iowa Oncology Research Association

    Des Moines, Iowa, United States

  • John Stoddard Cancer Center at Iowa Lutheran Hospital

    Des Moines, Iowa, United States

156 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Seneca Valley virus-001
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 Jan 2010
Primary completion
31 Jan 2013
Completion
15 Nov 2014
Last update posted
8 May 2017
Registered enrollment
59
Registry id
NCT01017601

Cross-registrations

Other registry (PDQ (Physician Data QueryCDR0000659547Other registry (CTRP (Clinical Trials Reporting SystemNCI-2011-01991

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.