Clinical trialNCT01042522UnknownPhase 2Interventional

Paclitaxel and Carboplatin or Bleomycin Sulfate, Etoposide Phosphate, and Cisplatin in Treating Patients With Advanced or Recurrent Sex Cord-Ovarian Stromal Tumors

SponsorGOG FoundationEnrollment63Ovarian Granulosa Cell TumorOvarian GynandroblastomaOvarian Sertoli-Leydig Cell TumorOvarian Sex Cord Tumor With Annular TubulesOvarian Sex Cord-Stromal TumorOvarian Sex Cord-Stromal Tumor, Not Otherwise Specified+1 more conditions

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This randomized phase II trial studies paclitaxel and carboplatin to see how well they work compared with bleomycin sulfate, etoposide phosphate, and cisplatin in treating patients with sex cord-ovarian stromal tumors that have spread to other places in the body and usually cannot be cured or controlled with treatment (advanced) or has returned (recurrent). Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving more than one drug (combination chemotherapy) may kill more tumor cells. It is not yet known which chemotherapy regimen is more effective in treating sex cord-ovarian stromal tumors.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Jubilee Brown
NRG Oncology
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

219 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Alaska Breast Care and Surgery Llc
Anchorage, Alaska, United States
Alaska Women'S Cancer Care
Anchorage, Alaska, United States
Anchorage Oncology Centre
Anchorage, Alaska, United States
Katmai Oncology Group
Anchorage, Alaska, United States
Providence Alaska Medical Center
Anchorage, Alaska, United States
Providence Saint Joseph Medical Center/disney Family Cancer Center
Burbank, California, United States
Olive View-University of California Los Angeles Medical Center
Sylmar, California, United States
University of Colorado Hospital
Aurora, Colorado, United States
Hartford Hospital
Hartford, Connecticut, United States
the Hospital of Central Connecticut
New Britain, Connecticut, United States
Sibley Memorial Hospital
Washington D.C., District of Columbia, United States
Northside Hospital
Atlanta, Georgia, United States
Augusta University Medical Center
Augusta, Georgia, United States
Northside Hospital-Forsyth
Cumming, Georgia, United States
Central Georgia Gynecologic Oncology
Macon, Georgia, United States
Lewis Cancer and Research Pavilion at Saint Joseph'S/candler
Savannah, Georgia, United States
Memorial Health University Medical Center
Savannah, Georgia, United States
Kootenai Health - Coeur D'Alene
Coeur d'Alene, Idaho, United States
Kootenai Clinic Cancer Services - Post Falls
Post Falls, Idaho, United States
Kootenai Cancer Clinic
Sandpoint, Idaho, United States
Illinois Cancercare-Bloomington
Bloomington, Illinois, United States
Saint Joseph Medical Center
Bloomington, Illinois, United States
Illinois Cancercare-Canton
Canton, Illinois, United States
Memorial Hospital of Carbondale
Carbondale, Illinois, United States
Sih Cancer Institute
Carterville, Illinois, United States
Illinois Cancercare-Carthage
Carthage, Illinois, United States
Centralia Oncology Clinic
Centralia, Illinois, United States
University of Chicago Comprehensive Cancer Center
Chicago, Illinois, United States
Cancer Care Specialists of Illinois - Decatur
Decatur, Illinois, United States
Decatur Memorial Hospital
Decatur, Illinois, United States
Crossroads Cancer Center
Effingham, Illinois, United States
Illinois Cancercare-Eureka
Eureka, Illinois, United States
Northshore University Healthsystem-Evanston Hospital
Evanston, Illinois, United States
Illinois Cancercare-Galesburg
Galesburg, Illinois, United States
Western Illinois Cancer Treatment Center
Galesburg, Illinois, United States
Northshore University Healthsystem-Glenbrook Hospital
Glenview, Illinois, United States
Northshore University Healthsystem-Highland Park Hospital
Highland Park, Illinois, United States
Sudarshan K Sharma Md Limited-Gynecologic Oncology
Hinsdale, Illinois, United States
Illinois Cancercare-Kewanee Clinic
Kewanee, Illinois, United States
Illinois Cancercare-Macomb
Macomb, Illinois, United States

179 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Bleomycin →Carboplatin →Cisplatin →Etoposide →Paclitaxel →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 8 Feb 2010
Primary completion: 12 Jun 2020
Completion: 2 Nov 2022
Last update posted: 25 Jan 2022
Registered enrollment: 63
Registry id: NCT01042522

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.