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Clinical trialNCT01097694CompletedPhase 2Interventional

Effects of cKit Inhibition by Imatinib in Patients With Severe Refractory Asthma (KIA)

SponsorBrigham and Women's HospitalEnrollment176Asthma
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to see whether a new investigational drug (Imatinib) may help improve asthma in people whose symptoms are not well controlled with high dose inhaled corticosteroid treatment.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

7 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • University of Alabama

    Birmingham, Alabama, United States

  • Brigham and Womens Hospital

    Boston, Massachusetts, United States

  • Washington University School of Medicine

    St Louis, Missouri, United States

  • Columbia University

    New York, New York, United States

  • Cleveland Clinic

    Cleveland, Ohio, United States

  • Temple University

    Philadelphia, Pennsylvania, United States

  • University of Wisconsin

    Madison, Wisconsin, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Imatinib →Placebo
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
30 Nov 2010
Primary completion
31 Aug 2015
Completion
31 Aug 2016
Last update posted
19 May 2017
Registered enrollment
176
Registry id
NCT01097694
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.