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Clinical trialNCT01110473CompletedPhase 1Interventional

ABT-348 as Monotherapy and in Combination With Azacitidine to Treat Advanced Hematologic Malignancies

SponsorAbbVie (prior sponsor, Abbott)Enrollment52Acute Lymphoblastic LeukemiaAcute Myelogenous LeukemiaB-cell Chronic Lymphocytic LeukemiaChronic Myelogenous LeukemiaMyelodysplasia
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to determine the safety, pharmacokinetics and maximum tolerated dose of ABT-348 as monotherapy and when given in combination with azacitidine.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

3 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Site Reference Id/investigator# 59324

    Scottsdale, Arizona, United States

  • Site Reference Id/investigator# 26523

    Atlanta, Georgia, United States

  • Site Reference Id/investigator# 26522

    Houston, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

ABT-348ABT-348 and azacitidine
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
30 Apr 2010
Primary completion
30 Jun 2013
Completion
30 Jun 2013
Last update posted
20 Nov 2017
Registered enrollment
52
Registry id
NCT01110473
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.