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Clinical trialNCT01123161TerminatedPhase 2/PHASE3Interventional

The Intravascular Cooling in the Treatment of Stroke 2/3 Trial

SponsorUniversity of California, San DiegoEnrollment120Stroke, Acute
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this trial is to determine whether the combination of thrombolysis and hypothermia is superior to thrombolysis alone for the treatment of acute ischemic stroke.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

31 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Austria
  • Medical University Innsbruck

    Innsbruck, Austria

Switzerland
  • Chuv

    Lausanne, Switzerland

United States
  • University of Alabama Hospital

    Birmingham, Alabama, United States

  • Cedars-Sinai Medical Center

    Los Angeles, California, United States

  • Hoag Memorial Hospital Presbyterian

    Newport Beach, California, United States

  • Scripps Mercy Medical Center

    San Diego, California, United States

  • University of California San Diego Health System

    San Diego, California, United States

  • University of Colorado Hospital

    Aurora, Colorado, United States

  • Swedish Medical Center

    Englewood, Colorado, United States

  • Hartford Hospital

    Hartford, Connecticut, United States

  • Yale University

    New Haven, Connecticut, United States

  • Gulf Coast Medical Center

    Fort Myers, Florida, United States

  • University of Florida

    Gainesville, Florida, United States

  • University of Miami, Jackson Memorial Hospital

    Miami, Florida, United States

  • Intercoastal Medical Group

    Sarasota, Florida, United States

  • St. Joseph'S Hospital

    Tampa, Florida, United States

  • Alexian Brothers Medical Center

    Elk Grove Village, Illinois, United States

  • Parkview Hospital

    Fort Wayne, Indiana, United States

  • Ruan Neurology Clinic and Research Center

    Des Moines, Iowa, United States

  • University of Louisville

    Louisville, Kentucky, United States

  • Henry Ford Health System

    Detroit, Michigan, United States

  • Michigan State University

    East Lansing, Michigan, United States

  • North Memorial Medical Center

    Robbinsdale, Minnesota, United States

  • Saint Louis University Medical Center

    St Louis, Missouri, United States

  • Columbia University Medical Center

    New York, New York, United States

  • University of Toledo Medical Center

    Toledo, Ohio, United States

  • Abington Memorial Hospital

    Abington, Pennsylvania, United States

  • Lehigh Valley Health Network

    Allentown, Pennsylvania, United States

  • Seton Medical Center Austin

    Austin, Texas, United States

  • Ut Southwestern

    Dallas, Texas, United States

  • University of Texas Health Science Center

    Houston, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Group1: IV t-PA and normothermia
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
30 Jun 2010
Primary completion
31 Jan 2015
Completion
31 May 2015
Last update posted
5 Apr 2017
Registered enrollment
120
Registry id
NCT01123161

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.