Clinical trialNCT01132807CompletedPhase 2Interventional

Chemotherapy Based on Positron Emission Tomography Scan in Treating Patients With Stage I or Stage II Hodgkin Lymphoma

SponsorAlliance for Clinical Trials in OncologyEnrollment164Lymphoma

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This phase II trial studies how well chemotherapy based on positron emission tomography (PET) scan works in treating patients with stage I or stage II Hodgkin lymphoma. Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells. Radiation therapy uses high energy x-rays to kill cancer cells. Giving combination chemotherapy together with radiation therapy may kill more cancer cells and allow doctors to save the part of the body where the cancer started. Comparing results of diagnostic procedures, such as PET scan, done before, during, and after chemotherapy may help doctors predict a patient's response to treatment and help plan the best treatment.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

David J. Straus, MD
Memorial Sloan Kettering Cancer Center
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

95 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Arizona Cancer Center at University of Arizona Health Sciences Center
Tucson, Arizona, United States
City of Hope Comprehensive Cancer Center
Duarte, California, United States
Yale Cancer Center
New Haven, Connecticut, United States
Ccop - Christiana Care Health Services
Newark, Delaware, United States
Lombardi Comprehensive Cancer Center at Georgetown University Medical Center
Washington D.C., District of Columbia, United States
M.D. Anderson Cancer Center at Orlando
Orlando, Florida, United States
Mbccop - Medical College of Georgia Cancer Center
Augusta, Georgia, United States
Kapiolani Medical Center for Women and Children
Honolulu, Hawaii, United States
Kuakini Medical Center
Honolulu, Hawaii, United States
Oncare Hawaii, Incorporated - Kuakini
Honolulu, Hawaii, United States
Oncare Hawaii, Incorporated - Lusitana
Honolulu, Hawaii, United States
Queen'S Cancer Institute at Queen'S Medical Center
Honolulu, Hawaii, United States
Straub Clinic and Hospital, Incorporated
Honolulu, Hawaii, United States
Castle Medical Center
Kailua, Hawaii, United States
Kauai Medical Clinic
Lihue, Hawaii, United States
Kapiolani Medical Center at Pali Momi
‘Aiea, Hawaii, United States
Oncare Hawaii, Incorporated - Pali Momi
‘Aiea, Hawaii, United States
John H. Stroger, Jr. Hospital of Cook County
Chicago, Illinois, United States
Louis A. Weiss Memorial Hospital
Chicago, Illinois, United States
Mount Sinai Hospital Medical Center
Chicago, Illinois, United States
Robert H. Lurie Comprehensive Cancer Center at Northwestern University
Chicago, Illinois, United States
University of Chicago Cancer Research Center
Chicago, Illinois, United States
Decatur Memorial Hospital Cancer Care Institute
Decatur, Illinois, United States
Evanston Hospital
Evanston, Illinois, United States
Cardinal Bernardin Cancer Center at Loyola University Medical Center
Maywood, Illinois, United States
Mcfarland Clinic, Pc
Ames, Iowa, United States
Siouxland Hematology-Oncology Associates, Llp
Sioux City, Iowa, United States
Ccop - Wichita
Wichita, Kansas, United States
Lucille P. Markey Cancer Center at University of Kentucky
Lexington, Kentucky, United States
Louisville Oncology at Norton Cancer Institute - Louisville
Louisville, Kentucky, United States
Norton Suburban Hospital
Louisville, Kentucky, United States
Mary Bird Perkins Cancer Center - Baton Rouge
Baton Rouge, Louisiana, United States
Mbccop - Lsu Health Sciences Center
New Orleans, Louisiana, United States
Medical Center of Louisiana - New Orleans
New Orleans, Louisiana, United States
Cancercare of Maine at Eastern Maine Medical Center
Bangor, Maine, United States
Greenebaum Cancer Center at University of Maryland Medical Center
Baltimore, Maryland, United States
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Baltimore, Maryland, United States
Union Hospital of Cecil County
Elkton, Maryland, United States
Dana-Farber/harvard Cancer Center at Dana-Farber Cancer Institute
Boston, Massachusetts, United States
Umass Memorial Cancer Center - University Campus
Worcester, Massachusetts, United States

55 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Bleomycin →Cyclophosphamide →DacarbazineDoxorubicin →Etoposide →Procarbazine →Radiation TherapyVinblastinePrednisone →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 May 2010
Primary completion: 29 Feb 2016
Completion: 31 Jan 2018
Last update posted: 14 Jun 2021
Registered enrollment: 164
Registry id: NCT01132807

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.