Clinical trialNCT01149915CompletedPhase 1Interventional

Study of Hypoxia-Activated Prodrug TH-302 to Treat Advanced Leukemias

SponsorThreshold PharmaceuticalsEnrollment40Acute Lymphoblastic LeukemiaAcute Myelogenous LeukemiaAdvanced MyelofibrosisChronic Lymphocytic LeukemiaChronic Myelogenous LeukemiaHigh-risk Myelodysplastic Syndrome

View the registry record on ClinicalTrials.gov

Summary

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Marina Konopleva, MD, PhD
M.D. Anderson Cancer Center
Principal InvestigatorKOL profile →
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of Texas M.D. Anderson Cancer Center
Houston, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Evofosfamide

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 30 Jun 2010
Primary completion: 31 Aug 2013
Completion: 31 Aug 2013
Last update posted: 7 May 2015
Registered enrollment: 40
Registry id: NCT01149915

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.