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Clinical trialNCT01179217CompletedPhase 3Interventional

A Phase III Safety and Efficacy Study of L-Glutamine to Treat Sickle Cell Disease or Sickle βo-thalassemia

SponsorEmmaus Medical, Inc.Enrollment230Sickle Cell AnemiaSickle ß0-Thalassemia
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this research is to evaluate the effects of L-glutamine as a therapy for Sickle Cell Anemia or Sickle ß0 Thalassemia as evaluated by the number of occurrences of sickle cell crises.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

31 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • University of South Alabama Medical Center

    Mobile, Alabama, United States

  • Phoenix Children'S Hospital Center for Cancer and Blood Disorders

    Phoenix, Arizona, United States

  • Kaiser Permanente

    Inglewood, California, United States

  • Children'S Hospital & Research Center at Oakland

    Oakland, California, United States

  • Children'S Hospital of Orange County

    Orange, California, United States

  • Harbor-Ucla Medical Center

    Torrance, California, United States

  • University of Denver School of Medicine Sickle Cell Treatment & Research Center

    Aurora, Colorado, United States

  • Howard University Hospital & Howard University

    Washington D.C., District of Columbia, United States

  • University of Florida

    Gainesville, Florida, United States

  • All Children'S Hospital

    St. Petersburg, Florida, United States

  • Children'S Healthcare of Atlanta at Egleston/emory University

    Atlanta, Georgia, United States

  • University of Illinois at Chicago

    Chicago, Illinois, United States

  • University of Louisville School of Medicine

    Louisville, Kentucky, United States

  • Sickle Cell Center of S. Louisiana, Tulane University School of Medicine

    New Orleans, Louisiana, United States

  • Johns Hopkins University

    Baltimore, Maryland, United States

  • Boston University Medical Center

    Boston, Massachusetts, United States

  • Children'S Hospital of Michigan

    Detroit, Michigan, United States

  • University of Mississippi Medical Center

    Jackson, Mississippi, United States

  • Children'S Mercy Hospitals and Clinics

    Kansas City, Missouri, United States

  • Children'S Specialty Center of Nevada

    Las Vegas, Nevada, United States

  • Comprehensive Cancer Center of Nevada

    Las Vegas, Nevada, United States

  • Cooper University Hospital

    Camden, New Jersey, United States

  • Brookdale University Hospital and Medical Center

    Brooklyn, New York, United States

  • Interfaith Medical Center

    Brooklyn, New York, United States

  • New York Methodist Hospital - Sc/thalassemia Program

    Brooklyn, New York, United States

  • Suny - Downstate Medical Center

    Brooklyn, New York, United States

  • the Brooklyn Hospital Center

    Brooklyn, New York, United States

  • Bronx Lebanon Hospital

    The Bronx, New York, United States

  • Presbyterian Blume Pediatric Hematology-Oncology Clinic

    Charlotte, North Carolina, United States

  • University of Tennessee Cancer Institute

    Memphis, Tennessee, United States

  • Virginia Commonwealth University

    Richmond, Virginia, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 May 2010
Primary completion
31 Mar 2014
Completion
31 Mar 2014
Last update posted
19 Aug 2020
Registered enrollment
230
Registry id
NCT01179217

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.