Dose Escalation, Combination Chemotherapy Safety Study of Birinapant (TL32711), in Subjects With Advanced or Metastatic Solid Tumors
Summary
The lay summary the sponsor registered on ClinicalTrials.gov.
Investigators
The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.
- Alex Adjei, MD, PhD
Roswell Park Cancer Institute
Principal Investigator - John N Nemunaitis, MD
Mary Crowley Cancer Research Center
Principal Investigator - Kyriakos P Papadopoulos, MD
South Texas Accelerated Research Therapeutics (START)
Principal Investigator - Lainie P Martin, MD
Fox Chase Cancer Center
Principal Investigator - Ravi Amaravadi, MD
University of Pennsylvania, Abramson Cancer Center
Principal InvestigatorKOL profile → - Zdenka Segota, MD
Holy Cross Hospital
Principal Investigator
A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.
Sites
7 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.
- Holy Cross Hospital
Fort Lauderdale, Florida, United States
- Barbara Ann Karmanos Cancer Center
Detroit, Michigan, United States
- Roswell Park Cancer Institute
Buffalo, New York, United States
- Fox Chase Cancer Center
Philadelphia, Pennsylvania, United States
- University of Pennsylvania Abramson Cancer Center
Philadelphia, Pennsylvania, United States
- Mary Crowley Cancer Research Center
Dallas, Texas, United States
- South Texas Accelerated Research Therapeutics (start)
San Antonio, Texas, United States
Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.
Drugs studied
The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.
Registration & key dates
Registry attributes as recorded on the ClinicalTrials.gov study record.
- Start
- 31 Oct 2010
- Primary completion
- 31 Oct 2013
- Completion
- 31 Mar 2014
- Last update posted
- 30 May 2016
- Registered enrollment
- 176
- Registry id
- NCT01188499
Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.