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Clinical trialNCT01196936Active, not recruitingPhase 2Interventional

Low-Dose Tamoxifen Citrate in Reducing Breast Cancer Risk in Radiation-Induced Cancer Survivors

SponsorUniversity of Alabama at BirminghamEnrollment84Breast Cancer
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Estrogen can cause the growth of breast cancer cells. Hormone therapy using tamoxifen citrate may fight breast cancer by blocking the use of estrogen by the tumor cells This phase IIb trial studies how well low-dose tamoxifen citrate works in reducing breast cancer risk in radiation-induced cancer survivors.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

13 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada
  • University Health Network, Toronto

    Toronto, Ontario, Canada

United States
  • University of Alabama at Birmingham

    Birmingham, Alabama, United States

  • City of Hope Medical Center

    Duarte, California, United States

  • University of Colorado, Anschutz Medical Campus

    Aurora, Colorado, United States

  • University of Chicago

    Chicago, Illinois, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, United States

  • University of Michigan

    Ann Arbor, Michigan, United States

  • University of Minnesota

    Minneapolis, Minnesota, United States

  • Mayo Clinic

    Rochester, Minnesota, United States

  • Wake Forest University

    Winston-Salem, North Carolina, United States

  • St. Jude Children'S Research Hospital

    Memphis, Tennessee, United States

  • Md Anderson

    Houston, Texas, United States

  • Seattle Cancer Care Alliance

    Seattle, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

PlaceboTamoxifen →
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
30 Sept 2010
Primary completion
11 Dec 2018
Completion
11 Dec 2028
Last update posted
5 Jan 2026
Registered enrollment
84
Registry id
NCT01196936
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.